Two men were injured and three horses died after a trailer carrying 10 of the animals overturned on the A303 eastbound carriageway, after colliding with a lorry.
Seven were sedated and removed by vets and expert animal rescuers but one was killed in the crash and two had to be put down.
Hampshire Fire and Rescue Service said the drivers of both vehicles were not seriously hurt.
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The forecast, covering the east of the region, for tonight and tomorrow.
The forecast for tonight and tomorrow in the west of the region.
Holly has the lunchtime forecast for the west of the ITV Meridian region.