Two men were injured and three horses died after a trailer carrying 10 of the animals overturned on the A303 eastbound carriageway, after colliding with a lorry.
Seven were sedated and removed by vets and expert animal rescuers but one was killed in the crash and two had to be put down.
Hampshire Fire and Rescue Service said the drivers of both vehicles were not seriously hurt.
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Friday's weather for the west of the Meridian region presented by Manali Lukha.
Friday's weather for the east of the Meridian region presented by Manali Lukha.
The wife of a missing man from Poole is appealing for the public’s help to find him almost two weeks after he disappeared.