A team of scientists at the University of Southampton have looked back through decade old clinical trials to shed new light on Alzheimer's disease.
The new findings come after the team examined brain tissue from people who took part in a clinical and safety trial of the AN1792 vaccine over 10 years ago. The vaccine aimed to remove the amyloid protein, a key component of the disease, from the brain.
A phase II of the trail vaccine was halted in 2002 when a small number of participants developed brain inflammation, and results from the trial showed no improvement in people’s symptoms. But the new research has shown that the vaccine was actually able to suppress the response to the disease.
“Our study not only adds to existing evidence that inflammation in the brain plays an important role in Alzheimer’s disease, but provides new hope for future clinical trials. Our research shows that amyloid can be removed from the brain without over-activating the brain’s immune system in the long-term, and this provides some hope for anti-amyloid treatments of the future.
More top news
Holly has all the latest weather details for Friday and the Bank Holiday weekend.
Several replicas of famous vehicles were damaged when a transporter caught fire, including a Batmobile from the 1966 TV show.
More than 100,000 cases of non-melanoma skin cancer are diagnosed in the UK each year.