London Gateway in Stanford-le-Hope, Essex, is a £1.5 billion "super port" which is expected to save British importers and exporters hundreds of millions of pounds every year from reduced transportation of goods across the UK.
Just 25 miles from the capital, it is the closest deep sea port to the UK's largest markets of London, Birmingham and Manchester. The container ship MOL Caledon is expected to arrive from South Africa at around 11pm.
London Gateway is Europe's largest logistics park with 9.25 million square feet of warehouse capacity, and it is thought the development will add £3.2 billion to the economy each year and 12,000 direct jobs.
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Their warning depends on whether negotiations for a post-Brexit Britain do not offer freedom of movement for people, capital and goods.
Wednesday morning's weather for the east of the region
Wednesday morning's weather for the west of the region