The RAF plane which has taken off for the Philippines from RAF Brize Norton will help those affected by the devastation caused by Typhoon Haiyan.
The C-17 transport plane filled with heavy duty vehicles and medical supplies is part of Britain's emergency response to the disaster.
The aircraft, being operated by No 99 Squadron, is due to land in the Philippines in around 24 hours time
Its load includes two JCB diggers, two Land Rovers and a forklift truck emblazoned with stickers reading "UK aid from the British people".
More top news
Wednesday morning's weather for the west of the region
Wednesday morning's weather for the east of the region
Tuesday night's weather for the west of the region