The Discovery New School in Sussex will become the country's first free school to close despite efforts to keep it open.
The school opened in September 2011 but was put in special measures when Ofsted inspectors rated it inadequate.
School governors were hoping for a reprieve when they met with government officials, but were told late last night that had failed.
It will close in April this year.
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Tuesday's weather for the west of the region
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Causes are thought to be climate change, fisheries, disease, and pollution.