Patients suffering from an inherited form of blindness have, for the first time, had their vision dramatically improved by gene therapy.
The first six people given experimental injections at the Oxford Eye Hospital were able to see better.
Researchers at the city's university and also at Southampton University say trials have shown promising results for the treatment of Choroideremia.
The Phase I clinical trial is funded by the Health Innovation Challenge Fund, a partnership between the Wellcome Trust and the Department of Health.
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Another cold and frosty night lies ahead, but the winter sunshine prevails for Friday.
Staying cold and frosty with plenty of winter sunshine.
Plenty of sunshine for some, but a little more cloud in the east and feeling cold