A man in his 60s has died after the lorry he was driving overturned on the A34.
Thames Valley Police is appealing for witnesses following the incident, which happened around 5am, on the northbound carriageway just north of the A343 at Wash Common.
The driver died at the scene. No one else was injured in the incident.
The northbound carriageway between the A343 and the A4 is expected to remain closed for several hours and the southbound carriageway will also be closed while the vehicle is recovered. Motorists are advised to avoid the area.
More top news
House prices in the south-east are expected to rise by 5% in 2015, fuelled by the recent change in Stamp Duty tax rules
Friday morning's forecast for the west of the region
Friday morning's forecast for the east of the region