Thames Valley Police is appealing for witnesses after a single vehicle road traffic collision, reported at 10.25am on the M40, today.
A black Jaguar S-type travelling on the M40 between junction 12 to 11, left the southbound carriageway to the nearside, going up the embankment and overturning.
The driver, a 61-year-old man, was pronounced dead at the scene.
Two other occupants, a 32-year old man and a girl, aged 7, were taken to the Horton General Hospital with minor injuries and have since been discharged.
Anyone who witnessed the collision or with information that may assist the investigation, should contact PS Keith Rayner or PC Graham Holt of the Thames Valley Police Roads Policing Team at Bicester on the non-emergency number 101.