The FTSE 100 has fallen 0.82% at the opening of trading on Monday, as the fallout from the Brexit vote continues to hit stock markets.
George Osborne said he would clarify whether he would run for leadership of the Conservative Party this week.
Speaking at a news conference in London on Monday morning, the Chancellor said: "There have been questions about the future of the Conservative Party and I will address my role within that in the coming days."
The Chancellor has said it is "perfectly sensible" to wait until there is a new prime minister before implementing an emergency budget.
Responding to a question by ITV News Business Editor Joel Hills about his earlier statement that Brexit would demand "an immediate response from government," George Osborne said that a financial contingency plan was in place and liquidity had been made available, but an emergency budget would be put in place in Autumn.
The Chancellor George Osborne has said the UK economy is "about as strong as it could be", as he looked to calm market fears following Brexit.
Speaking as financial trading started on Monday, Mr Osborne said the Leave vote in last week's EU referendum was "not the outcome I wanted" but said he "will do everything" he can to "make it work for Britain".
He added that "there will be an adjustment in our economy because of the decision that the British people have taken" but made no indication that there would be an emergency budget.
No sign of the emergency budget that the Chancellor said would be immediately necessary in the event of a Leave vote.
"I respect that decision and we're going to get on and deliver on that decision. But the impact on the economy will have an article on our public finances," he said.
His comments came after the pound suffered fresh losses during early trading on Asian markets on Monday morning.
Addressing the question of the free movement of labour following withdrawal from the EU, the chancellor said Britain is an "open and tolerant country" and he "will fight to keep it so".
The pound suffered fresh losses during early trading on Asian markets on Monday morning.
Sterling was quoted at $1.34 on Monday, down on Friday's close, when it dropped by more than 8% following the referendum result and slipped
Elsewhere, International Monetary Fund Managing Director Christine Lagarde said financial markets "vastly underestimated" the outcome of the vote.
But she added: "There was no panic and the central bankers did the job that they were prepared to do just in case, which was to put a lot of liquidity on the markets."
Chancellor George Osborne will seek to reassure financial markets on Monday morning following Britain's decision to leave the EU.Read the full story ›
Britain is headed for a "mild" recession, Nigel Farage has said - but denied it had anything to do with the UK's vote to leave the EU.
The pound plummeted to its lowest level in 35 years in the immediate aftermath of the referendum result, while stock exchanges around the world suffered a slump in prices as traders panicked in the face of economic uncertainty.
But the Ukip leader, who campaigned for some 25 years for Britain to withdraw from the bloc, told the Sunday Telegraph he believed that would have happened anyway.
"There's nothing new here," he said.
"I think we are going into a mild recession anyway, completely regardless of Brexit. Our growth forecasts are down. Our public-sector borrowing is still not under control at all and everyone forgets that sterling is in a bear market, declining since July 2014."
"Increased global opportunities" await outside the single market, he added, with "no reason" why Britain would not be reaping the benefits within two years.
Soros says that the European Union will struggle through the process of Brexit, with other countries wishing to follow suit.Read the full story ›
The City of London financial centre is at risk of losing its vital 'EU passport' after Britain voted to leave the EU, a European Central Bank boss has warned.
The 'passport' is relied upon by many London-based banks as it allows them to operate across the bloc without restrictions.
Speaking to France Inter radio, ECB Governing Council member Francois Villeroy de Galhau said if Britain chooses to leave the EU's single trade market then the City will not be able to keep that privilege.
"There is a precedent, it is the Norwegian model of European Economic Area, that would allow Britain to keep access to the single market but by committing to implement all EU rules," he added.
"It would be a bit paradoxical to leave the EU and apply all EU rules but that is one solution if Britain wants to keep access to the single market."
Brexit talks should be conducted as soon as possible to avoid uncertainties, he said.
Ratings agency Moody's said victory for Brexit would "herald a prolonged period of uncertainty" for the UK.Read the full story ›