Robert Huth's deflected close-range shot beat Man City keeper Joe Hart to give shock Premier League leaders Leicester an early 1-0 advantage against their title rivals at the Eitihad Stadium.
Reece Topley's career-best figures helped England restrict South Africa to 262 for seven in the second one-day international in Port Elizabeth.
Topley finished with four for 50 at St George's Park, but AB de Villiers (73) shared a century stand with JP Duminy as the hosts had to attune to the limitations of a slow and unpredictable surface after winning the toss.
England were left to contemplate a target well within the range of the power-hitters who piled up their overseas record 399 for nine in Bloemfontein three days ago, but perhaps awkward enough on this pitch.
Liverpool manager Jurgen Klopp missed the visit of Sunderland to Anfield on Saturday after coming down with suspected appendicitis.
The German undertook pre-match media duties on Friday but was subsequently taken ill and the club announced he would not be at Anfield for the Premier League fixture.
First-team duties were instead to be overseen by the remaining members of his backroom team, including assistant coaches Zeljko Buvac and Peter Krawietz, first-team development coach Pepijn Lijnders and goalkeeping coach John Achterberg.
England's Jos Buttler will play for Mumbai Indians in the Indian Premier League after being bought for £385,000.
The wicketkeeper-batsman, who has decided to play in the tournament after losing his Test spot to Jonny Bairstow, was the subject of a bidding war between Mumbai and the Kolkata Knight Riders in Saturday's auction.
The reigning champions stumped up the cash, meaning Buttler's first foray into the IPL will be based at the Wankhede Stadium.
Guus Hiddink maintains Chelsea's clash with Manchester United on Sunday is a big deal, despite the sides' seasons of struggleRead the full story ›
Chelsea midfielder Eden Hazard has revealed he sent a text message to Jose Mourinho after he was sacked apologising for his poor form.
The 25-year-old, who swept the board in the player of the year awards as Chelsea won the Premier League title last season, failed to replicate his stunning form this time around.
Mourinho paid the price in early December after being fired by Roman Abrahamovic. And the midfielder, who has yet to score in the Premier League this season, admits to feeling guilty.
"I sent him the message to say I was sorry he had gone and ... well ... just that I was sorry," he told the Guardian. "We'd enjoyed all that success together last season, but this time round we hadn't.
"I felt a little bit guilty because I'd been player of the year. I'd been one of the most decisive players, and this year I'd performed less well.
"I hadn't been at the same level. So I sent that text to Jose and he came back to me, wishing me all the best for the future."
NFL commissioner Roger Goodell has said it is a "realistic possibility" that there will be a UK-based franchise if the sport continues to grow in Britain.
For the third successive year, the 2016 season will see three games hosted in the capital, with Twickenham joining Wembley in staging International Series fixtures outside of the United States.
Speaking at a press conference in San Francisco ahead of Sunday's Super Bowl 50, Goodell said he expects more games to be taken to London and did not rule out the possibility of a team one day being based on British soil.
"We are considering playing more games in the UK, it's a balancing act with our schedule," he said.
"As you know, we're playing in two stadiums next year and that gives us a little bit more flexibility of how to do that. I believe the future will see more games in the UK.
"As far as a franchise, let's continue to grow, to see that excitement, enthusiasm, passion and support continue to develop. If it does, I think that's a realistic possibility."
Manchester United have declined to comment on reports that the club have held talks with representatives of Jose MourinhoRead the full story ›
Liverpool chief executive Ian Ayre has defended the club's owners Fenway Sports Group ahead of a proposed ticket price protestRead the full story ›