Scottish long-distance runner Freya Murray will replace Paula Radcliffe in the London 2012 Olympic marathon, reports Sky Sports News and Sky News Olympics Producer Lia Hervey.
Two-time Olympic gold medallist Daley Thompson has described Paula Radcliffe as "one of the greatest athletes we (Great Britain) has ever produced".
The world record marathon holder had to withdraw from the London 2012 Games with a foot injury on Sunday.
Paula Radcliffe if u do retire its as one of the greatest athletes we have ever produced. The only thing u lacked in you armory was luck
First time I smiled today was watching @l_armitstead claim silver in the womens road race - well done!
Paula Radcliffe continued: "Yes, I made more commitment than ever in preparation this year, two months away from the three most important people in my life.
Every single athlete out there makes the same commitments, puts their all into their preparation, and sadly I am not the only one to suffer heartbreak in trying to go after our goals. The most important thing is, as I always believe, to know that you did all you could in going after those dreams.
It is hard to know that had the Olympics been six weeks earlier I could have gone out there and run confidently knowing that I was in the best shape I had been in for a while, but I am by no means the first to experience something like this.
No-one tells us in advance where the limits of our own bodies lie, and pushing these limits is the only way we can ever achieve our highest goals and dreams. However hard today is, finally closing the door on that dream, at least I can know that I truly have tried absolutely everything.
As desperate as I was to be part of the amazing experience of the London Olympics, I don't want to be there below my best. If I can't be there and give it my best, then I would rather someone else who can do that is able to be there."
From the day when it was announced that London had won the bid, taking part and performing well in the London Olympic Games has been a major goal in my life. The goal of a fifth Olympics in my home country, what better? The chance to make amends to myself for bitter disappointments at the previous two Olympics. Through a lot of tough times it has kept me fighting, motivated and focused. That is why it hurts so much to finally admit to myself that it isn't going to happen.
– Paula RADCLIFFE
My sport is a beautiful sport, it gives so much fun and enjoyment, I believe it helps me to be a better person, and I have been very fortunate to experience some great success and have so many beautiful and happy memories. However, the downside is that it can break your heart and spirit many times over when your body is simply unable to match what your heart and brain want it to do. Sadly mine is not a career or a hobby where mind over matter can work when your body is hurt, nor where giving less than your best each day can ever work.
Team GB's Paula Radcliffe has pulled out of the Olympic marathon on medical grounds.