Klugman gained fame for playing sports writer Oscar Madison in the sitcom 'The Odd Couple', a role he also had played on Broadway.
'The Odd Couple', based on Neil Simon's play about two disparate divorced men forced to share an apartment, ran for five years on the ABC network. It started in 1970, but was never a hit during that time.
Only through repeats did Klugman and co-star Randall, who played neat-freak Felix Unger, leave their mark as one of US television's great sitcom teams.
Emmy award-winning actor Jack Klugman has died following a period of declining health. Klugman became a household name in America for his famous roles in 'The Odd Couple' and 'Quincy, M.E.'. He died at his home in Los Angeles aged 90.
His son, Adam Klugman said: "He went very suddenly and peacefully... he was there one minute and gone the next."