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According to the paper, nearly 2,000 nurses, managers and other senior NHS staff were spoken to, with more than 90 per cent of them saying he should step down.
Speaking to the Daily Mail, Roy Liley, a health policy analyst said:
Last night David Cameron defended Sir David, when he was questioned by reporters in India.
Relatives of those who died at the hospital have been placing pressure on the Prime Minister to sack Sir David, who was the head of the Trusts' Regional Health Authority at the time.
Speaking last night in India, Mr Cameron said Sir David was doing "a very good job".
"I would remind you of what the report says, that we should not be seeking scapegoats. I think to highlight David Nicholson in that way would be seeking a scapegoat."
Staffordshire Police has issued a statement regarding Stafford Hospital.
In it, Assistant Chief Constable Nick Baker said: "Staffordshire Police will be reviewing information brought to light by the Francis Inquiry in order to identify whether there is any potential for criminal damages."
A healthcare assistant at scandal-hit Stafford Hospital has been found to have dragged an elderly dementia patient around by his pyjamas and to have called him an animal.
Bonka Kostova was found to have physically and verbally abused the 73-year-old patient including telling him "you are no longer a human being but an animal" - or words to that effect.
Kostova was suspended from working at the Mid-Staffordshire NHS Trust pending today's tribunal at the Midwifery Council in central London.
Earlier this month Medical Director Sir Bruce Keogh announced an investigation into hospitals mortality rates.
Sir Bruce had identified an initial list of five organisations that had been outliers for two years on the Summary Hospital-level Mortality Indicator (SHMI), today he has announced the final list to be investigated:
- North Cumbria University Hospitals NHS Trust
- United Lincolnshire Hospitals NHS Trust
- George Eliot Hospital NHS Trust
- Buckinghamshire Healthcare NHS Trust
- Northern Lincolnshireand Goole Hospitals NHS Foundation Trust
- The Dudley Group NHS FT
- Sherwood Forest Hospitals NHS FT
- Medway NHS FT
- Burton Hospitals NHS FT
Health Secretary Jeremy Hunt is reported to have called on the police to investigate the hundreds of deaths attributed to the Mid Staffordshire hospital trust.
The Francis report into failings at Stafford Hospital, published on Wednesday, called for urgent reform of the NHS.
Hunt told the Daily Telegraph: “This was a public inquiry designed to help us understand why the system didn’t pick up what went wrong but I think it is absolutely disgraceful with all those things happening, whether it is doctors, nurses or managers, nobody has been held to account.”
Asked whether the findings should be handed to the police, he added: “It’s there for the police – and it’s there for the professional bodies, the General Medical Council and the Nursing and Midwifery Council, to look at and they should do that.”
A total of 11 NHS hospital trusts in England have now been identified as having high death rates, after yesterday's public inquiry into neglect at Mid-Staffordshire.
Five are already under investigation for similar reasons.
ITV News' Deputy Political Editor Chris Ship reports:
Robert Francis QC, the chairman of the inquiry into the scandal at Mid Staffordshire NHS Trust, told ITV News today that it was not his job to demand resignations.
He met the families of some of the people who died at Stafford Hospital to hear why they are calling for the head of the NHS to quit.
ITV News' Special Correspondent Geraint Vincent reports from Stafford:
Health Minister Norman Lamb has told ITV Daybreak that there has to be a proper process to ensure that people who fail in the health service are held to account.
He added: It was "utterly unacceptable what happened", and that we simply cannot have "rewards for failure".
The families of victims are calling for the resignation of NHS chief Sir David Nicholson, who was chief executive of the West Midlands Strategic Health Authority (WMSHA) between August 2005 and April 2006.
Following the publication of the Francis Report yesterday which highlighted the "unnecessary suffering" of patients at Mid Staffordshire NHS Foundation Trust, NHS chief Sir David Nicholson remains in his role today.
Victims' families have called for him to step down over the Stafford Hospital scandal, despite Sir David saying he is "not ashamed" of being in his job.
Frank and Janet Robinson, whose son John who died at Stafford hospital seven years ago, spoke to ITV Daybreak.
Frank said: "[Sir David] presided over a failing trust, no one has been able to account for this... I was always told the 'buck stops at the top'."
Latest ITV News reports
A public inquiry has blamed a failure 'at every level' of the NHS for the abuses at Stafford Hospital that resulted in hundreds of deaths.
The chair of the inquiry into Mid Staffordshire NHS made 290 recommendations to prevent the 'disaster' of Stafford Hospital occurring again.