- 60 updates
The Prime Minister said the "shocking truth is this precious principal of British life was broken in Mid Staffordshire".
David Cameron said a new post for the Chief Inspector of Hospitals would be created from the autumn.
The Prime Minister said there will be a new "single failure regime where the suspension of the board can be triggered by failures in care as well as failures in finance".
David Cameron apologised for the way the system had allowed "horrific abuse to go unchecked and unchallenged" for so long.
Speaking on behalf of the Government and the country he said: 'I'm truly sorry'.
David Cameron said the report's evidence of systemic failure means "we cannot say with confidence that failings of care are limited to one hospital".
In the scathing report Robert Francis QC attacked local health authorities and the trust board but he refused to blame any individual for failures at the trust.
However, the families of victims are calling for "accountability" and for the NHS Commissioning Board chief executive Sir David Nicholson to resign over the scandal.
Speaking as the report was published, inquiry chair Robert Francis QC said it was a "story of appalling and unnecessary suffering of hundreds of people."
Robert Francis QC paid tribute to the patients and relatives who brought the shocking facts of standards of care at Stafford Hospital to light.
He said the trust board was too focused on reaching targets, achieving financial balance and getting Foundation Trust status, whilst the medical community did not raise concerns until it was too late.
Robert Francis QC said the "appalling" conditions suffered by patients was caused by "serious failure" on the part of the trust board.
He said the trust failed to tackle an "insidious negative culture" including a tolerance of poor care standards, and failed to grasp the enormity of the problem.
The report says the trust's culture was one of "self-promotion rather than critical analysis and openness" and managers had "no culture" for listening to patients.
The poor leadership resulted in a "completely inadequate" standard of nursing being offered on some wards of Stafford Hospital.
Latest ITV News reports
A public inquiry has blamed a failure 'at every level' of the NHS for the abuses at Stafford Hospital that resulted in hundreds of deaths.
The chair of the inquiry into Mid Staffordshire NHS made 290 recommendations to prevent the 'disaster' of Stafford Hospital occurring again.