Senior Tory backbencher Bernard Jenkin has dismissed the idea that David Cameron could face a serious challenge to his leadership.
Speaking earlier to BBC Radio 4's Today programme, he said:
"It is for the birds.
"The idea that changing the leadership in the Conservative Party is another quick fix - we must avoid the idea there is some kind of silver bullet to get us out of the hole we are in."
"What this by-election shows is there is no such thing as the centre ground, there is no great pile of voters in the middle to be harvested cynically by politicians. What people are looking for are people to tell the truth,"
She said: "I'm afraid that there is a very large number of Members of Parliament on the Conservative benches now who come back from their constituencies every weekend in despair about the number of people who are resigning from the Party."
Asked what she thought Conservative voters were feeling, she said: "They feel hurt and they feel left out. They're told that they're old-fashioned and they think that they don't matter and that what they stand for, and what they believe in, doesn't matter.
"Those people who for decades have put their faith in the Conservative Party."