Organisations including Cancer Research UK and the Faculty of Public Health have pulled out of the Government's alcohol network in response to its decision to scrap a minimum unit price.
The network's co-chairman Nick Sheron, the head of clinical hepatology at the University of Southampton, also withdrew from the group, which forms part of the public health responsibility deal.
They said in a joint statement: "It is perfectly clear that MUP [minimum unit price] has fallen victim to a concerted and shameful campaign of lobbying by sections of the drinks industry who are putting profits before health and public safety.
"If we are serious about reducing early deaths from harmful drinking in this country we need leadership from Government, not the drinks industry, to implement legislation where there is good evidence it will work."
Prime Minister David Cameron has insisted the measures announced today would end the sale of very cheap alcohol, calling them "a positive step forward".
Mr Cameron said the Government is "effectively" introducing a minimum alcohol price as "we are saying it's going to be illegal to sell alcohol below the rate of duty plus VAT".
He continued: "There's a degree of legal uncertainty - it's been introduced in Scotland but it's still under legal challenge - and there's also question marks about the evidence behind it and how well it can work.
"So when we have more evidence about how it can work and when we've got more certainty about the legal issues I think it's an idea that has merit, that I'll be happy to consider again."
The Government's plans for a 45p minimum unit price for alcohol has been scrapped because there was not enough "concrete evidence" the plans would reduce the level of problem drinking without hitting those who drink responsibly.
Home Office Minister Jeremy Browne also ruled out a ban on multi-buy promotions due to a "lack of convincing evidence" that it would have a significant effect on consumption.
He said: "There has been much speculation about the Government's plans on minimum unit pricing. This will remain a policy under consideration, but will not be taken forward at this time.
"We do not yet have enough concrete evidence that its introduction would be effective in reducing harms associated with problem drinking ... without penalising people who drink responsibly."