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Andy Murray suffered his worst grand slam defeat since losing to Stanislas Wawrinka in the third round in New York three years ago.
Speaking at post-match press conference a visibly disappointed Murray said: "I don't think I was playing poorly. I got to the quarter-finals of a slam which isn't easy.
"I would have liked to have played a little bit better but I've had a good run the last couple of years. It's a shame I had to play a bad match today."
Reigning US Open champion Andy Murray crashed out of this year's tournament in the quarter-finals after suffering a defeat in straight sets to Switzerland's Stanislas Wawrinka.
The ninth seed beat Britain's number one 6-4 6-3 6-2.
Andy Murray is fighting to stay in the US Open after losing the first two sets of his quarter final match against Switzerland's Stanislas Wawrinka.
The defending champion lost the opening two sets 6-4 6-3.