Woman's ovaries 'reawakened'

A woman has given birth to a baby after having her ovaries "reactivated" through a new technique developed in Stanford University in the US and St Marianna University School of Medicine, Japan.

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Experts warn ovary method is 'very much experimental'

Several fertility experts have warned women to be cautious in their hopes after an woman's ovaries were 're-awakened' leading to her delivery a healthy baby boy in December.

Dr. Sherman Silber of the Infertility Center of St. Louis criticized the approach, saying he has had success by using drugs rather than surgery to treat the condition. He also disagreed with the researchers' explanation as to why this treatment worked.

Experts warn ovary method is 'very much experimental' Credit: Katie Collins/PA Wire

The new results, experts cautioned, must be viewed as preliminary.

"It shows a lot of promise (but) I don't think it's even close to being ready" for routine use, said Dr. Mark Sauer of the Columbia University Medical Center in New York. Dr. Amber Cooper of Washington University in St. Louis called the technique "very much an experimental method."


  1. Lawrence McGinty

Complicated process brings hope to infertile women

It is a fairly amazing process, and so far has been 100% successful in producing one child in Japan so there is one very satisfied customer.

Some women stop producing eggs early on, like the patient in Japan, but now it seems that these follicles can bereawakened.

The process is quite complicated - they remove some of the ovary through keyhole surgery, they then cut it into tiny little bits because there is a natural mechanism in the ovaries that stops them producing too many eggs at once.

By cutting it up you overcome that mechanism, they also give it a drug which switched off a mechanism which stops the follicles developing into eggs.

They then put them back into the woman, give her hormonal treatment to mature them and then take them out and use a conventional IVF treatment to produce a baby.

It is very early days yet, as the researchers admit, but it looks like it could be promising for some women.

Scientists induce egg production in infertile women

Scientists at Stanford University of Medicine have developed a radical new treatment to stimulate egg production in infertile women who suffer from 'primary ovarian insufficiency' a condition that causes early menopause.

Dr Aaron Hsueh and Yuan Cheng, who made the discovery, explained their work in a video produced by Stanford University.

The scientists said the treatment could be a "real breakthrough" in treating infertile women, but that more studies, particularly on women whose infertility is caused by other factors, is needed.

Baby born after pioneering ovary reactivation

A woman suffering from a condition called primary ovary insufficiency has given birth to a healthy baby after taking part in a pioneering study and clinical trial.

The baby born using the IVA technique, developed by researchers at Stanford University. Credit: Kazuhiro Kawamura

Using a technique called IVA ("in vitro activation") researchers removed the woman's ovaries, treated them outside the body, and re-implanted them near her fallopian tubes. The woman was then treated with hormones to stimulate the ovary follicles in which eggs develop.

Although the method was developed specifically for women suffering from primary ovary insufficiency, the researchers at Stanford University plan to investigative whether the technique can be used to treat other types of infertility.

Woman gives birth after ovaries 'reawakened'

A woman has given birth to a baby after having her ovaries "reactivated" through a new technique developed in Stanford University in the US and St Marianna University School of Medicine, Japan.

One baby has been born because of the new echnique, and another woman is expecting. Credit: Press Association

Doctors in the US and Japan developed the technique to remove the ovaries, activate them in the laboratory and re-implant fragments of ovarian tissue.

The technique, reported in Proceedings of the National Academy of Sciences, has resulted in one baby being born, whilst another is expected.


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