Former Spurs and Chelsea manager Andre Villas-Boas is set to take over at Schalke this summer, according to reports in Germany.
Villas-Boas will step down at Zenit after the Russian club's final match of the season this weekend after refusing to consider a contract extension over a lack of first-team investment.
The Portuguese coach won the Russian Premier League title last season and guided Zenit to the Russian Cup trophy earlier this month with an emphatic 4-1 victory over CSKA Moscow.
Last week, Schalke confirmed that manager Andre Breitenreiter would be leaving the club after they finished the season three points behind fourth-placed Borussia Monchengladbach, failing to qualify for the Champions League.
Andre Villas-Boas has announced he will leave his position as Zenit St Petersburg coach at the end of the season.
The former Chelsea and Tottenham boss, currently serving a six-game ban following an altercation with a match official, led Zenit to the Russian Premier League title last term.
But the Portuguese said he had turned down the offer of a new contract.
"Talking about a contract extension, when we last met with you I said that the club had made me an offer at the end of last season, I have refused and at the end of the season I will leave the club," he said at a press conference ahead of his side's meeting with league leaders CSKA Moscow.
Zenit lie third in the table after seven games of the season, six points behind CSKA.
Andre Villas-Boas has been sacked as manager of Tottenham, the club has announced.
A Tromso supporter was removed from his seat during Tottenham Hotspur's 2-0 Europa League win after Spurs manager Andre Villas-Boas took offence to chants of "You're getting sacked in the morning".
Reidar Stenersen Jr, a 29-year-old hairdresser, claims he subjected Villas-Boas to the chants while the score was still goalless.
The Spurs boss, who is under pressure following a poor run of results including a 6-0 hammering at the hands of Manchester City, took offence to the abuse and notified a steward.
The official subsequently asked Stenersen, who was sat behind the Spurs dugout, to move to another stand but he refused, and instead walked out to watch the remainder of the game in a nearby pub.
Stenersen suggested the current scrutiny the manager is under may of contributed to what he called a "petulant" reaction.
"I know he is under a lot of pressure so I think my words hit him, even though I am only a little guy in little Tromso. He was being a bit petulant. This is the same thing that can be sung by 60,000 at the Emirates Stadium or other grounds."
To watch highlights of Tottenham's 2-0 win over Tromso, visit ITV Football
Chelsea manager Jose Mourinho will come face-to-face with his former understudy Tottenham manager Andre Villas-Boas when the two teams meet at White Hart Lane today.
Villas-Boas, 35, worked under the Blues boss for seven years at Porto, Inter-Milan and Chelsea but his relationship with his former mentor has since broken down.
Speaking ahead of the clash, the Spurs boss said: "I don't lose any sleep. We had a great personal and professional relationship before. We don't have that now."
Meanwhile, Mourinho stayed uncharacteristically silent when asked about his relationship at a pre-match press conference on Friday, "I've got nothing to say", he told journalists.
The match between Tottenham and Chelsea will kick-off at 12.45pm.
Andre Villas-Boas expects UEFA to take action against Inter Milan after their supporters appeared to racially abuse Tottenham players on Thursday night.
"It's a very sensitive situation," Spurs manager Villas-Boas said of the chanting. "UEFA set out to act on that situation.
"It was very, very easy to hear the chanting so I am sure that UEFA will act on it.
"It's difficult for Inter Milan because it is something that in some way has happened before.
"It doesn't mar the game but it is something that should have been avoided."
It has been reported that Tottenham players were tonight subjected to racist chants by Inter Milan supporters, who were also seen waving an inflatable banana.
Spurs lost 4-1 after extra-time on the night but progressed to the Europa League quarter-finals on away goals after the tie finished 4-4 on aggregate.
Monkey chants appeared to be aimed at several Tottenham players, notably goalscorer Emmanuel Adebayor, while a fan was seen with an inflatable banana.
Andre Villas-Boas has been appointed the new manager of Tottenham Hotspur.
The former Chelsea boss, who was sacked from the Stamford Bridge club last season, replaces Harry Redknapp at White Hart Lane.
The club confirmed the deal on their official Twitter account.