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Novak Djokovic has ended Sir Andy Murray's winning streak of 28 consecutive ATP Tour Matches, beating him in the Qatar Open final.
Djokovic defended the title, winning 6-3 5-7 6-4, yet Murray remains the world number one.
Djokovic won in two hours and 54 minutes.
Both players will now head to Melbourne for the Australian Open which begins on January 16 and is the year's first Grand Slam.
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Andy Murray beat Novak Djokovic in straight sets in the World Tour Final - sealing his position as world number one for the rest of 2016.
The Wimbledon champion, who shot to the top of the world rankings a fortnight ago, would have been knocked off his spot if Djokovic had won.
It is the fifth title in a row the Scotsman has won, bringing his winning run to 24 matches.
Speaking at the O2 Arena in London, Murray, 29, said: "Obviously it's a very special day.
"Playing against Novak in a match like this, we've played grand slam finals, Olympics - it's been a tough rivalry.
"I've lost many of them - I'm very happy I managed to win today.
"To finish the year number one is something I never expected."
Andy Murray fought with gritted teeth and weary limbs to hold onto his number one dreams and reach his first final at the ATP World Tour Finals.
Four days after he took three hours and 20 minutes to defeat Kei Nishikori, Murray was on court for 18 minutes longer in a 5-7 7-6 (7/5) 7-6 (11/9) victory over fourth seed Milos Raonic - breaking the tournament record for longest match for the second time.
Raonic twice broke Murray when he served for the match and saved three match points but could not take the one chance that came his way in a remarkable deciding tie-break that eventually went the way of the home favourite.
Murray cut a fatigued figure throughout and looked exhausted by the end, and the question must now be how much energy he will have left for Sunday's final.
Jamie Murray and his Brazilian partner Bruno Soares will finish the year as the world's top-ranked doubles pair.
The duo went into the ATP World Tour Finals trailing Nicolas Mahut and Pierre-Hugues Herbert by 575 points but overhauled them on Thursday courtesy of their third win.
The French duo were eliminated after losing both their first two matches but could still have prolonged the race by winning their final group match against Henri Kontinen and John Peers.
But they lost 6-7 (5/7) 6-4 10-4, meaning Murray and Soares cannot be overtaken.
Murray became the first British player ever to be officially ranked world number one when he moved to the top of the individual doubles rankings earlier this year, pipping brother Andy to the honour.
Soares could now finish the year with that title if he and Murray win the title on Sunday.
Mahut only needed one victory to become the first French player to finish a year ranked number one but the Wimbledon champions have been well below their best at the O2 Arena.
Murray and Soares will play either Feliciano Lopez and Marc Lopez or Raven Klaasen and Rajeev Ram in the semi-finals on Saturday.
Andy Murray defeated Stan Wawrinka to surge through to the semi-finals of the ATP World Tour Finals, closer to a showdown with Novak Djokovic.
After winning his opening two matches against Marin Cilic and Kei Nishikori, the Scot knew a set against Wawrinka would be enough.
He went one better, clinching a 6-4 6-2 victory to set up a rematch of the Wimbledon final against Milos Raonic on Saturday.
Should Murray come through that, and Djokovic defeat Nishikori in the other semi-final, then Sunday's final would also be a straight shoot-out for world number one.
It was also a 22nd consecutive victory for Murray, equalling his career-best streak from this summer, which included titles at Queen's and Wimbledon and Olympic gold.
The Scot said: "The first set was tight, there weren't many chances either way. I just managed to get the break. In the second set, I'd already qualified, Stan obviously needed to win so it was a bit easier for me to play more freely than him.
"I played a very solid match and obviously I'm very happy to be through to the semis."