Barcelona are set to be without Lionel Messi for around three weeks after he ruptured an adductor muscle in his right leg in the 1-1 draw at home to Atletico Madrid on Wednesday night.
The Argentinian maestro appeared to suffer the injury after tussling for possession with Atletico defender Diego Godin and was replaced by Arda Turan with 58 minutes gone.
Worse was to follow for Barca as Angel Correa then equalised for the visitors, jinking past Javier Mascherano and steering a shot past Marc-Andre ter Stegen and in off a post.
The news about Messi was a further blow to Barcelona, who were unable to make any inroads into Real Madrid's three-point lead at the top despite Ivan Rakitic heading them in front against Diego Simeone's side in the 41st minute.
The club confirmed the time-frame of Messi's injury in a tweet from the club's official account, and coach Luis Enrique told the Spanish media: "Losing Messi is a loss to us and a loss to football. With Leo we are stronger, but we are still strong without him."
Barcelona midfielder Sergio Busquets will sign a new five-year contract with the Spanish champions.
A statement published on Barca's official website said Busquets, 28, would commit his future to the Catalan club until June 30, 2021 by agreeing a new deal on Thursday.
The new contract includes the option of a further two-year extension, depending on the number of games the Spain international plays.
Busquets graduated from Barca's academy in 2008 and has since made 390 competitive appearances for the Nou Camp outfit, winning LaLiga six times and the Champions League thrice.
The son of former Barca goalkeeper Carles Busquets, he became a world champion with Spain in 2010 and helped his country defend their European title two years later.
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Barcelona have completed the signing of Spain striker Paco Alcacer from Valencia on a five-year deal.
The Catalans will pay €30million for the forward who has 13 caps for his country.
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Ajax goalkeeper Jesper Cillesen has confirmed his transfer to Barcelona, allowing Claudio Bravo to join Manchester City.
The Dutch international tweeted a photo of himself in a Barcelona shirt along with the message "Dreams come true".
Barcelona have confirmed defender Thomas Vermaelen has joined Roma on loan for the upcoming season.
The 30-year-old Belgium centre-back travelled to Italy for a medical over the weekend and Barca announced on Monday that a deal had been finalised between the clubs.
A club statement read: "Barcelona and Roma have reached an agreement for the loan of Thomas Vermaelen for the 2016/17 season. The agreement includes an option for Roma to buy the player at the end of that season."
Vermaelen has had a difficult time at the Nou Camp since joining from Arsenal for £15million in 2014, with injuries limiting him to just 21 games in all competitions.
The former Ajax defender, who signed a five-year contract with the Spanish club, had to wait until the final match of his first season to make his Barca first-team debut after undergoing thigh surgery.
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Barça XI: 1.Ter Stegen 5.Sergio 6.Denis 7.Arda 9.Suárez 10.Messi 12.Cámara 14.Mascherano 17.Munir 22.Aleix Vidal 24.Mathieu
Barcelona have signed their second French defender of the week by completing a deal for Lucas Digne from Paris Saint-Germain.
The left-back, who spent last season on loan at Roma, has signed a five-year deal with the Catalan giants.