Two penalties from Eoin Doyle helped Cardiff condemn relegated Blackpool to a full Championship season without an away victory thanks to a 3-2 victory, matching the club's record set in 1909.
Joe Mason's early strike fired the hosts into the lead, with Doyle doubling their advantage after Henry Cameron had fouled Aron Gunnarsson.
Andrea Orlandi's goal gave the visitors hope of mounting a comeback, but Doyle killed off their chances following Miles Addison's foul on Mason before Peter Clarke's late consolation.
Blackpool are already 2-0 down at Cardiff, meaning they are set to go through the entire season without an away victory.
Blackpool chairman Karl Oyston has denied a Football Association charge of misconduct.
The much-maligned Oyston is said to have called a supporter a 'retard' in a text message exchange.
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Blackpool chairman Karl Oyston has been charged by the Football Association for text messages in which he called a supporter "a retard".
Back in December it emerged that Oyston had sent a series of text messages to fan Stephen Smith, who he told to "enjoy the rest of your special needs day out".
Oyston later apologised for his part in the exchange, however the FA announced on Monday that the messages allegedly constituted five breaches of its rules and the Tangerines chief now has until 6pm on March 30 to respond to the charge.
"It is alleged that the misconduct constituted five breaches of FA rules, and that during the text message exchange, Mr Oyston used abusive and/or insulting words towards a supporter of Blackpool FC," the FA said in a statement.
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Kim Bo-kyung and Harry Maguire scored their first goals for Wigan in a vital 3-1 victory at fellow Championship strugglers Blackpool.
South Korea international Kim, who joined from Cardiff earlier in February, opened his Latics account just before the break and centre-back Maguire, on loan from Hull, added a second midway through the second half.
Winger James McClean then sealed the visitors' victory late on to leave Blackpool - who scored a late consolation through Gary Madine - routed to the bottom of the table, 15 points from safety.
I can't believe anyone is still here at Bloomfield Road. Another embarrassing, shameful and heartbreaking game to watch.
At Bloomfield Rd for the basement battle! Hoping there will be goals. Neither team prolific but both poor defensively http://t.co/RXkdbzBSYk