A Japan Airlines flight to Tokyo returned to the US amid a suspected fuel pump issue on the Boeing 787 Dreamliner.
It is the latest setback for Boeing's new aircraft after a lithium ion battery problem grounded the fleet in January and a blaze on an Ethiopian Airlines plane at Heathrow last week.
Japan Airlines spokeswoman Carol Anderson said Flight 007 returned to Boston's Logan Airport last night "as a standard precautionary measure" to check a maintenance message indicator showing the possible fuel pump problem.
A spokesman for the US Federal Aviation Administration said the incident was not an emergency.
Ethiopian Airlines has become the world's first carrier to resume commercial flights with Boeing's 787 Dreamliner aircraft, Reuters reports.
Video footage of Boeing's next generation aircraft, the 787 Dreamliner.
Qatar Airways are offering Boeing 787 Dreamliner commercial flights from Doha to the UK.
The airline will be become the first to operate regular scheduled flights to the UK with Boeing's next generation aircraft.
The new service to London Heathrow is due to commence from December 13.
A Boeing 787 Dreamliner made an emergency landing in New Orleans on Tuesday because of a mechanical problem.
The brand new United Airlines jet carrying 184 people onboard was flying from Houston to Newark, New Jersey, when it was forced to divert and land.
It came on the same day that US aviation regulators ordered the entire fleet of 787 jets to be inspected for a possible fuel line problem.
The Boeing Dreamliner safety checks were ordered after two non-US carriers experienced fuel leaks.
Japan's All Nippon Airways said it had reported a fuel leak to the FAA and Boeing on Sunday.
ANA spokesman Yoichi Uchida said the carrier found the fuel leak on October 23.
He said the airline completed inspections of all 16 ANA Dreamliners on Sunday, and that the work did not interrupt scheduling.
The US Federal Aviation Administration has ordered safety checks on all Boeing's 787 Dreamliners currently in service to confirm that fuel line connectors have been properly installed, Boeing has said.
The inspection will affect its fleet of 33 jets.
It follows concerns that some connectors have not been properly installed.
The plane is due to start flying from Heathrow next week.
The FAA requirement, due to be issued today, "makes mandatory inspections already recommended by Boeing," the company said.