Hopes of renegotiation of the UK's place in the European Union is an "absolute illusion", Boris Johnson has said.
The only way for the UK to have any control over its "borders, immigration arrangements, and democracy" is for it to leave the EU, the former London mayor said.
The Vote Leave campaigner also hit out at European Commission president Jean-Claude Juncker's claim that "out is out" if Britain votes for Brexit, and that the "Brussels bureaucrat" had "absolutely no intention of allowing this country [UK] to have any further change in its arrangements and obligations to the EU". This he said, left voters with no option but to "vote leave".
Mr Johnson made his comments on the final day of campaigning as he toured the country on behalf of Vote Leave.
Boris Johnson was heckled by a teenage Remain supporter as he campaigned in Ashby in Leicestershire.
"You'll be to blame Boris mate," the activist said as he questioned the mayor of London's decision to support the campaign to leave the EU.
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Boris Johnson has claimed Britain is on the verge of an "extraordinary event in the history of our country".
With less than 24 hours to go until polls open, the former London mayor and Leave campaigner, told supporters in Maldon, Essex:
I do think that we are on the verge, possibly, of an extraordinary event in the history of our country and indeed in the whole of Europe.
It's all going to about getting our supporters out to vote and if we do it I really think tomorrow can be independence day.
Johnson is embarking on whirlwind tour of England in a final push to win backing for Brexit.
He was earlier pictured at a fish market.
Boris Johnson has denied claims that his campaign to leave the EU has been divisive.
The former London mayor told Good Morning Britain: "I believe in immigration, I just believe in control."
He added: "What we're talking about today and tomorrow as we make this decision is who runs this country, how our democracy works."
With just days left until the EU referendum, leading Vote Leave campaigner Boris Johnson is travelling around Britain to persuade voters to back the UK leaving the EU.
To do that, he must assuage voters' worries about personal finances, which are growing according to recent polls.
ITV News National Editor Allegra Stratton reports:
Vote Leave campaigner Boris Johnson has said he is pro-immigration and supports an amnesty for illegal immigrants who have been in the UK for more than 12 years.
Speaking at an EU referendum campaign event today, Mr Johnson said: "I am the proud descendant of Turkish immigrants.
"I am in favour of an amnesty for illegal immigrants who have been here for more than 12 years unable to contribute to this economy, unable to pay taxes, unable to take proper part in society."
Mr Johnson said an amnesty would be humane and economically rational, and would enable Britain to "take back control" of immigration.
He added that introducing an Australia-style immigration points system would enable Britain to deal "fairly and justly" with every part of the world and "neutralise" extremists opposed to immigrants.
In a 2013 interview, Boris Johnson says he wants Britain to be able to 'trade freely with our European friends'.Read the full story ›
Boris Johnson said half the money the UK receives back from the EU remains 'under control of bureaucrats in Brussels'.Read the full story ›
Boris Johnson, Andrea Leadsom and Gisela Stuart are making their way to the ITV EU Referendum Debate.
They will represent the Vote Leave campaign.
SNP leader Nicola Sturgeon, Angela Eagle and Amber Rudd will appear on behalf of Vote Remain.