Paul Pogba will start Manchester United's last Champions League group game against CSKA Moscow but Zlatan Ibrahimovic will not feature.
Pogba was sent off against Arsenal and is suspended for Sunday's Manchester derby, while United are handling Ibrahimovic with care after his return from knee ligament damage.
Luke Shaw could appear for just the third time this season, Sergio Romero replaces David De Gea in goal and the injury list contains Nemanja Matic, Michael Carrick, Marouane Fellaini, Phil Jones and Eric Bailly.
Man United squad to face CSKA: Romero, Pereira, Lindelof, Rojo, Smalling, Valencia, Young, Darmian, Blind, Shaw, Tuanzebe, Pogba, Matic, Herrera, McTominay, Mata, Lingard, Mkhitaryan, Martial, Rashford, Lukaku.
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