England seamer James Anderson will miss the first Test against India next month as he continues his recovery from an injury to his right shoulder.
Anderson, England's record Test wicket-taker with 463 scalps in 119 matches, was ruled out of the forthcoming series against Bangladesh due to a recurrence of the problem which first flared up over the summer, when he sustained a stress fracture to the area.
His rehabilitation will now stretch into the India series, where he will be absent for the first Test in Rajkot, which gets under way on November 9.
England captain Alastair Cook announced the news, saying: "I don't think he'll be there for the start. He might be ready to do some training, but he won't be ready for the first Test match."
England boss Andrew Strauss expects Eoin Morgan to captain the one-day side in India despite withdrawing from the Bangladesh tour because of his security fears.
Morgan led England to seven wins from 10 ODI matches this summer but, along with fellow batsman Alex Hales, he will be absent from the Bangladesh trip in October.
Strauss says the call to miss out on Bangladesh will not be held against the pair, and he expects Morgan to resume his leadership role on the tour of India in November.
"Right from the start we said there are not going to be any recriminations," England and Wales Cricket Board director Strauss told BBC Radio 5 Live's Sportsweek programme.
"It's not like these guys are going to be black-listed and their names will not be put forward for selection. They absolutely will be.
"Both have done outstanding jobs for England over the last 12 months, especially Eoin Morgan whose captaining has been sensational.
"Of course, we can't give any guarantees because the situation might change on the ground in Bangladesh.
"Someone might come in and do unbelievably well, but the intention is for Eoin to come back in as captain and Alex will be in the mix for selection as well."
England will take an unassailable 2-1 lead to The Oval for next week's final Investec Test after wrapping up a 141-run victory over Pakistan at Edgbaston.
Hometown hero Chris Woakes and Steven Finn provided the telling surge, with four wickets for one run between them just before tea, as England bowled the tourists out for 201.
They were completing an improbable fightback, having conceded a 103-run first-innings deficit, and did so ultimately with 13.1 overs to spare - despite the determination of young opener Sami Aslam (70) and then the late sting of an improbable 50 stand between numbers 10 and 11 Sohail Khan and Rahat Ali.
England international Jos Buttler is set for a spell on the sidelines after Lancashire announced the wicketkeeper-batsman has sustained a fractured left thumb.
The 25-year-old was struck by a bottom edge from Ben Cox's bat while keeping during the Lightning's T20 Blast win over Worcestershire on Friday.
He was in visible discomfort for the remainder of Worcestershire's innings, but the blow did not stop him blasting a 20-ball half-century, Lancashire's fastest fifty in Twenty20 cricket.
Lancashire cricket director and head coach Ashley Giles confirmed after the match that Buttler would undergo an X-ray and now his county and the England and Wales Cricket Board have provided an update on his condition.
A statement read: "Lancashire and England's Jos Buttler received a blow to his left thumb during Friday night's NatWest T20 Blast match against Worcestershire Rapids at New Road.
"X-rays later revealed he sustained a small stable fracture which will be managed conservatively."
James Anderson has been omitted from England's squad for the first Test with Pakistan.
The England and Wales Cricket Board announced Anderson had not recovered from a shoulder injury sustained in the third Test with Sri Lanka last month.
Jos Buttler had been in contention to replace Nick Compton, but was also not named in the 12-man squad.
Instead, Yorkshire batsman Gary Ballance was recalled, while Middlesex seamer Toby Roland-Jones receives a first call-up.
England captain Alastair Cook said: "Jimmy has been touch and go for a while, he is making really good progress but it is the selectors' view that he just wont be quite ready for that first Test, hopefully for the second."
The first Test begins on July 14 at Lord's.
England needed Alastair Cook back urgently at Lord's, after their top order hit trouble in his injury-enforced absence.Read the full story ›
England captain Alastair Cook has backed Chris Woakes to perform in Ben Stokes' absence.Read the full story ›
James Anderson and Jonny Bairstow were the driving forces as England began their Test summer with an emphatic innings victory inside three days over Sri Lanka at Headingley.
Only bad weather and a maiden half-century from Kusal Mendis remotely threatened to inconvenience England, and Anderson - who finished with a match haul of 10 for 45 - and wicketkeeper Bairstow, with nine catches to add to his 140 runs, were having none of it.
The first of three Tests was wrapped up by an innings and 88 runs, shortly after tea, when Sri Lanka were bowled out for 119 after losing their last seven wickets for 26.
England's bowlers managed only two wickets, both again from James Anderson, on the third morning at Headingley as Sri Lanka tried to hold up their hosts' victory charge in the first Investec Test.
Following on 207 runs behind after being hustled out for 91 by Anderson and Stuart Broad the previous evening, Sri Lanka's lot was once again unenviable to keep England's seamers at bay in difficult conditions.
But a poor weather forecast for Saturday's remaining two sessions, and the jarred left knee which meant Ben Stokes was unlikely to bowl, offered minor respite - and Kusal Mendis rode his luck before rain brought an early lunch, with his team on 77 for two.
England's victory push was set to get under way 15 minutes late, after overnight rain, on day three of the first Test against Sri Lanka at Headingley.
The tourists face an unenviable task, in likely tough conditions again, to have any chance of avoiding defeat over the remaining three days - after being bowled out for 91 on Friday and then following on.
Just two more deliveries were possible on the second evening, with Sri Lanka one for none second time round but needing another 206 just to make England bat again.
A poor forecast on Saturday offered them possible hope of some respite from a rampant home attack, led by James Anderson and Stuart Broad.