David Cameron said he agrees with Sir John Major after the former prime minister suggested the EU was often seen as showing a "lofty disdain" for British concerns.
During a speech in Germany, Sir John put the chance of a British exit from the European Union at "just under 50%" and warned it would become a reality unless there is genuine reform.
When asked about Sir John's speech, Cameron said, "I agree with what he said."
"When countries in Europe have difficulties that need to be addressed, Europe needs to have the flexibility to address them," he said, before describing Sir John's speech as powerful, important and timely.
Opting into the controversial European arrest warrant (EAW) will prevent Britain becoming a "honeypot" for European fugitives, the Home Secretary has said.
Opponents of the EAW cite concerns it is too easy for UK citizens to be extradited and some Conservative backbenchers have hinted at a revolt when the proposal comes to a vote in the Commons.
ITV News Political Correspondent Libby Wiener reports:
The shadow home secretary has pledging Labour's support in a promised Commons vote on opting back in to the European Arrest Warrant.
Yvette Cooper said she was "pleased" that the Home Secretary was supporting the measure as Labour believed it was needed to protect Britain's borders and public safety.
Failing to do so would "much harder to deport foreign criminals and would also make it more difficult for us to bring British citizens who have committed crimes back to our country to face justice", she said.
Former immigration minister Damian Green said it would be "really dangerous" if Britain failed to opt back in to the warrant:
We would be the country in Europe where all Europe's criminals and terrorists would be inclined to come, because not only would we not be able to get terrorists back from other countries as quickly as we can now ... but also rapists, murderers, child molesters and so on would think Britain is probably the place to go where you'd have most chance of not being convicted of crimes you committed in the rest of Europe.
David Cameron has said he is angry about the European Union demand for a £1.7 billion surcharge.
I'm angry at the sudden presentation of a €2bn bill to the UK by the EU. It's an appalling way to behave and I won't be paying it on Dec 1st
Ukip leader Nigel Farage has defended his decision to join forces with a member of a right-wing Polish party to save his grouping in the European Parliament.
The Eurosceptic Europe of Freedom and Direct Democracy (EFDD) group escaped disbandment after it recruited Polish Congress of the New Right (KNP) member Robert Iwaszkiewicz, keeping up its tally of MEPs from at least seven member states.
Farage insisted that he had found nothing in Iwaszkiewicz's background to suggest that he was an extremist.
Asked about the MEP's reported comment that there were "quite a few wives around who'd be brought back down to earth" if their husbands hit them, Farage told BBC Radio 4's The World At One, "I think that comment was a joke."
Foreign Secretary Philip Hammond has said it is vital that the European Union raises one billion euros (£800 million) to help fight Ebola.
Speaking ahead of a meeting of EU foreign ministers, he said: "There is a major health crisis here. We've got a very short window to get on top of it and prevent the uncontrollable spread of this disease."
David Cameron's influence as Prime Minister would be "zero" if Britain left the EU, the president of the European Commission said.Read the full story ›
The European Union (EU) has promised to reinforce passenger screening for Ebola at airports in countries with the disease and coordinate a common approach for the deadly virus at EU entry points.
EU health chief Tonio Borg said the World Health Organisation and the EU examine reports that the screening in Liberia, Sierra Leone and Guinea is not good enough. If lapses are evident, Mr Borg said international measures will be taken to strengthen controls.
The PM believes freer Trans-Atlantic trade links could add £10 billion to the UK economy. So why are there widespread protests to stop them?Read the full story ›
Whether it is a Yes or No vote, the referendum result will be followed closely around the world, especially regarding the possible "domino effect" in Europe.
Scotland's decision is of particular interest to Flemish nationalists in Belgium and the Catalans in Spain.
ITV News Europe Editor James Mates reports from Brussels: