Six children have died after a school minibus crashed in to a truck in Rochefort, south-west France.
Local authorities in Charente-Maritime confirmed the news on Twitter, adding two people required urgent medical attention and nine others were being supported following the incident.
Accident transport scolaire #Rochefort. 6 décédés, 2 personnes en urgence relative, 9 pris en charge.
France's Prime Minister Manuel Valls spoke of "pain and compassion" after the crash "took six young lives", appearing to suggest that all the victims were students.
Alain Vidalies, French secretary of state for transport, also expressed "terror and great sadness" at the news.
Effroi et très grande tristesse face au terrible accident de car scolaire à Rochefort. Toutes mes pensées vont aux proches et aux familles.
Segolene Royal, Ecology Minister said the government "fully supports the families of victims" in the accident, adding that work was starting on the site.
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A man arrested carrying two handguns at Disneyland Paris told police he had the weapons because he feared for his safety, a source told the AFP news agency.
The source also said initial investigations did not suggest the incident was linked to terrorism.
Papers found on the suspect suggested he lived in Paris.
Police are continuing to search for his girlfriend.
The 28-year-old man arrested with handguns at a hotel in Disneyland Paris was carrying the weapons in his luggage, a spokesman for the amusement park said.
During a routine security screening checkpoint at one of our hotels, weapons were discovered in a guest's luggage through our X-ray machine.
The police were immediately notified and the individual was arrested.
We continue to work closely with the authorities, and the safety and security of our guests and cast members is our utmost priority.
A woman has been held at Disneyland Paris soon after police arrested a man with two handguns in one of the amusement park's hotels, a French police official has said.
The woman is believed to be the partner of the 28-year-old man, who was reportedly carrying a copy of the Koran when he was arrested at the New York Hotel this afternoon.
She is said to have fled after the man was stopped by security staff when his bag passed through an X-ray machine at the hotel
The official said the woman didn't appear to be armed and the police are not looking for other suspects.
France is under a state of emergency after Islamic extremist attacks in Paris in November killed 130 people.