Vincenzo has been transformed from a patient so sick he could not wash his face to a man who strides confidently with a gleam in his eye.
A look at organ donation rates around the world and how the UK compares.
In a one hour special the Tonight programme investigates the lives of the 10,000 Brits on waiting lists for an organ transplant.
During ITV's From The Heart week to raise awareness for organ donation, record numbers of people applied to join the NHS Organ Donation Register.
On Feb 13th, when an ITV special programme on organ donation was broadcast, a record 48,000 applied online to join the register, with nearly 147,000 throughout the week.
Sally Johnson, Director of Organ Donation and Transplantation at NHS Blood and Transplant said:
"We could not have foreseen the unprecedented numbers of people who responded to the call to join the Organ Donor Register.
"So to each and every person who is now on the Register and crucially, has told their family, thank you."
Every day in the UK three people die waiting for an organ transplant.
Each day this week on ITV News in our series From the Heart we have been highlighting how many lives could be saved if the desperate shortage of organ donors across Britain was ended.
ITV News Medical Editor Lawrence McGinty is at Papworth Hospital and has been speaking to transplant surgeons about a device which helps keep transplant patients alive until they receive a donor organ:
Since the launch of the From the Heart campaign on Monday 120,000 people have signed up to the donor registry.
In the latest in ITV News' series of reports, From The Heart focuses on the extraordinary medical technology that keeps patients alive - while they wait for the heart transplant they so desperately need.
As ITV News' medical editor Lawrence McGinty reports from Papworth Hospital, the shortage of donors means that it is sometimes a long wait:
As part of the ITV1 special 'From the Heart' X Factor winner Alexandra Burke described how her family kept her mother's illness from her during the 2008 final of the X Factor.
Alexandra's mother Melissa needs a kidney transplant, and spends 8 hours a day on a dialysis machine, as she waits for one.
The severe shortage of Black, Asian and Minority Ethnic organ donors mean that donors from these communities have to wait three times longer to get the transplant they need.
Tune into itv1 now, #haveaheart such a brilliant cause ????????
The NHS website where people can register to be organ donors is experiencing difficulties due to an "overwhelming demand" from people watching the ITV 'From the Heart' Tonight special.
Our website is currently struggling with people wanting to register. You can text SAVE to 84118 #fromtheheart
Please bear with us, there is an overwhelming demand on our website. You can also call 0300 123 23 23 to register #fromtheheart