A student whose dyslexia is so severe she did not learn to read or write until she was 10-years-old has achieved an A* in her English literature GCSE.
Holly Sayer also gained an A in English language in her results which totalled 10 GCSEs including two A*s, three As, two Bs and two Cs.
The 16-year-old, who studied at the Ark Charter Academy in Portsmouth, Hampshire, said: "There was a lot of stress involved and now I am really happy."
"Personally, I'm quite heavily dyslexic and yet my favourite subject is English. "The only way I could get round it was through the extra-curricular help that I was given."
She added: "I feel just a little bit chuffed, I think the hard work has most certainly paid off."
Sayer, who hopes to one day become a film director now hopes to complete her A-levels and go to Cambridge University or an Ivy League college.
Schools Reform Minister Nick Gibb said that changes to the exam system that are behind today's "variable" GCSE results are in the best interests of the pupils.
An exams system had developed that worked against the best efforts of teachers and the best interests of pupils.
These results show our plan for education is correcting that.
The number of children now taking exams at the right time, the number studying for academic GCSEs and the higher standards achieved are hugely encouraging.
Fortismere twins Agnes & Hester Girling each earned a whopping 11 A*s. Wowzers! Well done! http://t.co/RysPs1Z327
Hampstead School twins Kenny and Taiwo celebrate with As in maths. They both want to be videogame developers. http://t.co/GmY1hkQFM8
The biggest impact on this year's GCSE results have stemmed from changes that mean students did not sit exams early, compared to previous years when pupils could take GCSEs multiple times, exam chiefs suggested.
This year, only a teenager's first attempt at an exam would count in school league tables, so schools that had traditionally made use of the winter exam season, entered pupils early, or made use of resitting are likely to have seen the greatest changes.
There has been a significant amount of change to the system this year and although UK level figures are relatively stable we expect more schools and colleges to see volatility in their results. The extent of this volatility will depend on how much change from their usual practices they experienced and how they adapted.
Entry patterns are very different this year. We have seen a dramatic decline in the number of entries from 15-year-olds, which is largely due to a change in the school accountability measure, where a candidate's first entry counts in performance tables, and the move to end-of-year exams in England.
As we would expect, where the change in entry patterns is greatest, such as the sciences, English and maths, we have seen some impact on results. But despite these changes and the potential for increased centre volatility, candidates can be confident that standards have been maintained.
Today's GCSE results show that girls once again lead pass rates at grade C and above, with 73.1% of girls' entries scoring A*-C compared with 64.3% of boys'.
However, official results showed that boys are beginning to close the gap at A*, with 5.2% of entries scoring the top grade compared with 8.1% of girls'. The difference of 2.9 percentage points is down from three percentage points last summer.
The proportion of GCSE exam students awarded at least a C grade has risen for the first time in three years, official figures show.
Just over 68.8% of exam entries scored A*-C - up 0.7 percentage points on last summer, statistics published by the Joint Council for Qualifications (JCQ) show.
In maths, 62.4% of students were awarded an A*-C grade - a significant 4.8 percentage points on last year's results.
Exam chiefs suggested that changes to this year's entries, including fewer lower-performing 15-year-olds taking the GCSE early, are behind the hike.
In contrast, 61.7% of English entries scored a C or higher, down 1.9 percentage points from last summer.
The drop - believed to be the biggest in the qualification's history - could be down to strong candidates taking advantage of the chance to sit the exam last winter, the JCQ suggested.
The proportion of entries awarded an A* - the highest grade - has dropped to 6.7% from 6.8% last year. It is the third year in a row that the number of students achieving the top pass rate has fallen.
Schools preparing to receive their GCSE results today have been told to expect "variable" grades.
There are particular concerns among some headteachers about English and maths grades, according to initial reports.
The potentially unpredictable results are said to be due to significant alterations to the qualifications this year.
Brian Lightman, general secretary of the Association of School and College Leaders, which represents a large proportion of secondary heads, said: "We are getting some individual reports of volatility, but we don't know about overall trends yet.
"Some schools have seen surprises. Some schools have seen results which are lower than expected."
Education Secretary Michael Gove said he wanted "schools to be able to nurture creative talent in every child" after announcing that exams in arts subjects are set to become tougher.
I am passionate about great art, drama, dance, music and design, and I am determined to ensure every child enjoys access to the best in our culture. I also want all schools to be able to nurture creative talent in every child.
That is why I am delighted that new high-quality qualifications in creative and cultural subjects will be made available to all students.
They will now have the chance to take these new qualifications from September 2016.
A major reform of the exams system will see GCSEs and A-levels in arts subjects such as music and drama undergo a radical overhaul in a bid to make the courses tougher, it has been announced.
A total of nine GCSEs and six A-levels will be reformed under the Government's plans, in a move that ministers say will give pupils in England access to "high-quality" qualifications in creative subjects.
The Department of Education said that from September 2016 the following new GCSEs will be available in schools; art and design, music, drama, dance, citizenship, computer science, design and technology, PE and religious studies
They will be taught alongside new GCSEs in history, the sciences, geography and foreign languages - the subjects contained in the Government's English Baccalaureate (EBacc).
Groups promoting the arts, design and religious education previously expressed criticism that too much attention was put on exams in traditional subjects and creative disciplines had been left out.
The Association of School and College Leaders General Secretary Brian Lightman is due to call on the government to respond unanswered questions over reforms to qualifications such as the GCSEs, after warning that students and teachers faced another three years of turmoil.
ASCL Curriculum and Qualifications Specialist Sue Kirkham, who is leading a seminar on the reforms at the conference today in Birmingham, said:
We don't yet know what format these examinations will take, what the precise content of the syllabus will be in most subjects or what kinds of questions will be asked.
All of this needs to be known before teachers and school leaders can plan effectively in order to prepare from them. Also, awarding bodies need to be trusted to brief teachers ahead of the changes so that teachers can begin to prepare.