Liberal Democrat Michael Moore has been replaced as Scottish Secretary by the party's chief whip Alistair Carmichael.
This is not going to be a Conservative Cabinet reshuffle, but among the junior ranks there will be some tinkering.
Chloe Smith was just 27 when elected MP in Norwich and became David Cameron's youngest minister when she was promoted two years later.
Speaking to Tom Bradby on the Agenda the Prime Minister has said that the reshuffle in the Cabinet is an opportunity to "bring on fresh talent."
– David Cameron
What you do is refresh the team and I've got a talented bunch of MPs and it's right some of them should be serving in the government.
It's an opportunity to bring forward some fresh talent. There was a mixture of people from all sorts of backgrounds and walks of life. The main thing is are they qualified to do the job and I think they will prove that.
- The Agenda with Tom Bradby will be broadcast on ITV tonight at 10.35pm
David Cameron will speak to Tom Bradby on the Agenda tonight after a busy day rearranging his Cabinet.
As well as the reshuffle, the Agenda will also be looking at the new WikiLeaks film the Fifth Estate.
Downing Street has tweeted with the full list of the government reshuffle:
The wife of Robert Syms, who was a Conservative whip, has taken to Twitter to air her anger after he lost his position in the reshuffle.
The self-proclaimed "David Cameron cheerleader" launched a scathing attack on the Prime Minister after her husband's demotion:
PM just fired father of my kids over the phone. Gave up chairmanship of a cttee to be a whip, worked hard and was widely acknowledged...
to be a good whip. He was utterly gracious and took it like a man, I am beyond furious. Loyalty counted for nothing.
Luckily for Dave he'll continue to be super loyal. I'd be fixing up drinks with Afriye, Crouch, Wollaston, Norman. No not really.
MPs have taken to Twitter to express their pleasure at the new Cabinet roles after the government's reshuffle:
Congratulations to @swilliamsmp for joining the Government as a Minister in CLG and Dan Rogerson as a Minister in DEFRA!
Congratulations to Lib Dem colleagues- Dan Rogerson MP joining the Government as Minister at DEFRA, and @swilliamsmp as a Minister at DCLG.
Absolutely delighted to have been asked by @david_cameron to take both the sports and equalities briefs
Liberal Democrat MP Norman Baker has moved from his role as crime prevention minister to a new Home Office job.
Hugh Robertson, formerly sports minister, has been appointed as Foreign Office minister.
Liberal Democrat peer Baroness Kramer has been appointed transport minister.
She lost her Richmond Park seat to Zac Goldsmith in 2010.
Conservative MP Helen Grant has been moved sideways from the Ministry of Justice.