Championship leaders Hull will be without skipper Michael Dawson for up to a month due to a hamstring injury.
The Tigers have responded brilliantly to relegation, with Steve Bruce's side currently top of the standings following an impressive 11-match unbeaten run.
Much of that success has been down to City's sturdy defence - the best in the Championship - but that could be destabilised by an injury to key man Dawson.
The former Tottenham captain had to be taken off 37 minutes into Saturday's 1-1 draw at Bristol City and the club have confirmed the 32-year-old could now be out for a month.
A statement on the club's official website said:
Scans have confirmed that Michael Dawson sustained a grade two hamstring injury during Saturday's 1-1 draw with Bristol City.
The injury is expected to keep Dawson out of action for three to four weeks.
Substitute Shaun Maloney slotted home a second-half equaliser as Sky Bet Championship leaders Hull were made to fight all the way for a 1-1 draw by Bristol City at Ashton Gate.
While the visitors showed the greater quality, their hosts left the pitch to a rousing ovation having battled from first whistle to last.
Kieran Agard fired the Robins in front after 39 minutes after Andrew Robertson brought down Elliott Bennett on the right side of the penalty area.
Luke Freeman's inswinging free-kick caused havoc and the hosts appealed for handball before Agard pounced on the loose ball to net with a left-footed short on the turn.
Hull had to wait until the 73rd minute to equalise when Harry Maguire broke clear onto a Mohamed Diame flick and produced an emphatic right-footed finish with only Frank Fielding to beat.
Hull City midfielder Jake Livermore is set to return to action on Tuesday night's in his side's Capital One Cup tie against Swansea.
The former Spurs youngster will be in The Tigers' squad - likely on the bench - for the first time since May.
Livermore was suspended towards the end of last season after testing positive for cocaine following a match.
Following the death of his son, Livermore used the drug after battling depression and avoided a longer ban as the Football Association took the extenuating circumstances into account.
Jake Livermore returns to training at Hull City after escaping a potential two-year ban for failing a drugs testRead the full story ›
Hull City midfielder Jake Livermore will not be banned after he tested positive for cocaine last season.
The Football Association originally suspended the former Spurs player after the substance was found in his system following the death of his newborn son.
Livermore could have faced up to a two-year ban for the positive test, but the mitigating circumstances were taken into account during a personal hearing last week.
West Ham have completed their third deal of the day by signing striker Nikica Jelavic from Hull City.
The Croatian international is linking up with his former national team boss, Slaven Bilic, at Upton Park.
Hull midfielder Jake Livermore was reportedly struggling with the death of his child when he tested positive for cocaine last seasonRead the full story ›
Sam Clucas and Chuba Akpom got Hull's Championship season off to a strong start with debut goals in a 2-0 win over Huddersfield at the KC Stadium.
Former Chesterfield winger Clucas opened the scoring after 38 minutes when his first effort from an Ahmed Elmohamady cross came back off Huddersfield keeper Alex Smithies and he netted the rebound.
Arsenal loanee Akpom added a second when he shot high into the goal after working space on the right side of the area.
Norwich City have completed the signing of Hull City midfielder Robbie Brady, the Premier League club have announced.
The former Manchester United youngster has penned a three-year deal at Carrow Road.
West Brom have signed defender James Chester from Hull City, the two clubs have confirmed.
Former Manchester United youngster Chester has penned a four-year deal at The Hawthorns.