A hospital spokesman has confirmed that four people have died in the shooting attack in Tel Aviv.
Gil Fire, the deputy director of the Tel Aviv Sourasky Medical Centre, said ten people were taken to the centre for treatment.
Four people have "moderate to severe wounds" but are in a stable condition while two more are "in decent condition".
Two gunmen opened fire near a popular open-air market in the centre of the city.
One of the gunman is reportedly undergoing surgery in hospital after being shot by security forces and the other gunman is in custody.
Report by ITV News' Middle East Correspondent Geraint Vincent
Four of those wounded in the Tel Aviv shooting are said to be in a critical condition in hospital, it has been reported.
Three people were killed when two gunmen opened fire close to the popular open-air Sharona market in Tel Aviv.
Initial reports showed there were at least two gunmen in the Tel Aviv shooting attacks, an Israeli police spokeswoman has said.
Meirav Lapidot said both were "neutralised", which can mean either killed or detained.
Another spokeswoman Luba Samri said there were reports of shooting in two locations close to the popular open-air Sharona market.
One of the attackers is being treated in hospital, she added.
Israel has been struggling to cope with eight months of Palestinian attacks that have killed 28 Israelis and two Americans.
About 200 Palestinians have been killed during that time, most identified as attackers by Israel.
Witnesses have described the moment of terror when at least one gunman opened fire in Tel Aviv.
Three people are dead after attacks in two locations close to the popular open-air Sharona market.
Jerusalem resident Avraham Liber said it looked like one of the gunmen was sitting down at a cafe.
He said the shooter got up and started firing at point blank range at people sitting down.
Meital Sassi told Channel 10 TV she was out with her family celebrating her son's birthday when she heard shots and "immediately understood it was a terror attack".
"We ran like lightning with the baby and the stroller ... I yelled at people who didn't understand what was happening to run," she said.
Three people have been killed in a shooting in Tel Aviv when at least two gunmen opened fire, according to Israeli police.
There were reports of shooting in two locations close to the popular open-air Sharona market on Wednesday night, spokeswoman Luba Samri said.
Channel 10 TV said reports indicate that at least one of the attackers was disguised as an ultra-Orthodox Jew with black coat and hat.
Another spokeswoman, Meirav Lapidot, said initial reports showed there were "at least two terrorists".
She said both were "neutralised", which can mean either killed or detained.
Police are searching the area to make sure there are no other attackers or possible bombs.
At least nine people have been wounded in a shooting in central Tel Aviv.
One person is in a critical condition, Israeli police said, adding the shooting was an apparent attack aimed against Israelis.
The incident occurred in an area of trendy cafes and restaurants very close to the central military headquarters and Defence Ministry compound.
The attack was the first following in lull after almost daily street attacks by Palestinians against Israelis which began in October and lasted several months.
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Israeli security forces shot dead a Palestinian man today after he reportedly stabbed two police officers in Jerusalem.
The alleged attacker was shot by officers after an assault on two officers outside the walled Old City.
Israeli police described the man as a "terrorist," saying he had "stabbed and lightly wounded" his victims.
"The team responded by gunfire and neutralised the terrorist," police spokeswoman Luba Samri said.
In a continued state of heightened violence, 164 Palestinians and 28 Israelis have been killed since October.
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