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Two patients who sparked a suspected Mers outbreak at a Manchester A&E unit have tested negative for the virus.
Dr Rosemary McCann, North West Deputy Director of Health Protection for Public Health England, said: "PHE can confirm that two individuals were tested for MERS-CoV in Manchester. These cases were separate and unrelated. The results of both tests were negative."
There have been 316 tests for MERS since 2013, with all being negative.
Manchester Royal Infirmary A&E has re-opened as the hospital investigates two suspected cases of Mers.
Central Manchester University Hospitals issued a statement confirming that one patient suspected to have the virus has been moved to another hospital and said there is "no significant risk" to public health.
This afternoon, we confirmed that we are currently investigating two patients for suspected Middle Eastern Respiratory Virus Syndrome - Coronavirus Infection (MERS-COV).
Both patients were isolated for on-going management of their condition while tests took place.
One patient has now been relocated to North Manchester General. Results of the tests are still pending.
Manchester Royal Infirmary A&E is open to the public.
We would like to reassure our patients and the general public that there is no significant risk to public health.
As Manchester Royal Infirmary deals with two suspected cases of Mers, an expert in viruses has described the risk to the general public as "extremely low."
Dr Derek Gatherer, a lecturer at the University of Lancaster, said: "Outside hospitals the risk to the general public is extremely low and the outbreak ought not to cause concern."
The World Health Organisation defines Mers risk as being confined to those hospital workers not wearing appropriate personal protective equipment and working within two metres of a case in a ward or those patients in the same room or ward as a confirmed case, or those who have contacted respiratory secretions from a case.
The hospital closed its accident and emergency department while it investigates two patients suspected to have the virus.