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Ed Miliband has told supporters that the IFS assessment of party manifestos showed the Tories were committed to "extreme spending plans".
"They have also confirmed that Britain would be facing the deepest cuts over the next three years of any advance country in the world," the Labour leader said during a visit to Nuneaton in Warwickshire.
Miliband continued: "It is a plan so extreme that far from protecting the NHS they would end up cutting the NHS.
"It is a plan so extreme that it wouldn't mean three years of the good life, it would mean three more years of the hardest of times."
Ed Miliband has unveiled a new poster campaign with Labour's proposals for a "better plan for the NHS".
ITV News Political Correspondent Carl Dinnen reports from Nuneaton:
Labour has accused the Tories of planning the biggest spending cuts in any of the world's advanced economies since the Second World War.
Ed Miliband warned the Conservatives plan to balance the books would result in 20,000 fewer police officers and the closure of 1,000 sure start centres.
He will tell a rally in Leeds: "It is a plan so extreme that International Monetary Fund figures show Britain would be facing the deepest cuts over the next three years of any advanced country in the world.
"It is a plan so extreme that far from protecting the NHS they would end up cutting the NHS. It is a plan so extreme that it wouldn't mean three years of the good life, it would mean three years of hard times.
"Maybe not for some of the rich and powerful, who have done so well with the last five years of the Tories. But it would mean hard times for the working families of Britain, who put in the hours, pay their taxes and play their part."
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Ed Miliband have promised an emergency round of nurse recruitment and funding for 1,000 extra training places in the first year of a Labour government.
"To save the NHS we cannot wait. With A&E in crisis, staff shortages and hospitals weighed down by large deficits, this plan has to start immediately.
"First things first, the next Labour government will start by saving the NHS", Mr Miliband said.
Ed Miliband has said his party would invest £2.5bn into the NHS within the first year of a Labour government.
"An investment not for an NHS that stands still but one that keeps up with the challenges of time", he said.
Prime Minister David Cameron is "a mortal danger to the NHS", Labour leader Ed Miliband has said in Manchester.
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