Marathon world record-holder Paula Radcliffe will run the first event to be staged at London's Olympic Stadium since the 2012 Games later today.
Radcliffe, who was unable to compete at the London Olympics due to injury, will join a host of sporting stars including Olympic gold medallists Sir Chris Hoy and Victoria Pendleton, who are more used to cycling than running.
They will be among the 12,500 people taking part in the five-mile (eight-kilometre) National Lottery Anniversary Run, in which competitors will complete the final 328 yards (300m) on the Olympic Stadium's track.
Radcliffe has predicted the event would "recapture the spirit of the London 2012".
Responding to the claims of MPs in a post-Games review, the London Legacy Development Corporation said it will not jeopardise the "long-term legacy" of the Olympic Park by rushing to repay its debts.
We have to look at the longer term impact and to balance that with our obligations not just to the Lottery but also to the Greater London Authority in terms of receipts going back.
While there is a drive to maximise receipts and get the taxpayers' money back, no one would want us to act as some kind of rapacious developer at the risk of jeopardising the long-term legacy of the Park.
It is a balance and we have to work that through over the coming months.
– LLDC chief executive Dennis Hone
Also responding to the Public Accounts Committee's review, the Culture department said there are "many lessons learned" from London 2012 which the Government was "sharing for future projects".
The Government is committed to delivering a tangible, lasting legacy from the Games and work is well under way on this.
We have been crystal clear that the lottery has an entitlement to receive £675 million from land sales from the Olympic Park, that is bound by a legal agreement between the Government and Mayor of London. We will respond to the PAC report in full in due course.
The embarrassing sight of empty seats at London 2012 and the availability of tickets for the general public was another concern raised by MPs in their post-Games review.The Public Accounts Committee (PAC) said it was "a shame that so few tickets for popular events were available to the UK public".
Only 51% of tickets for the men's 100 metres final were available to the British public, and less than half of tickets for the track cycling, MPs said.
"International sports bodies and media organisations wield a lot of power and it cannot be easy for individual event organisers to push back at their demands," the PAC said.
"But," it added, "Learning from the experience of the London Games, the Government, possibly alongside other governments and event organisers, should challenge demands for large numbers of accredited seats."
A post-Games review from MPs has raised doubts that £2bn worth of London 2012 funding from the National Lottery will be repaid.
The donation ensured the Lottery would be reimbursed from future returns from developments at the Olympic Park, which was developed using the public funds it boosted.
The Public Accounts Committee (PAC) said it was "not clear" that the Lottery's interest is being "adequately promoted and protected" by the London Legacy Development Corporation (LLDC), which is in charge of securing the economic future of the Park.
The MPs suggest the Government should develop "a mechanism" to ensure the LLDC's decisions are transparent and prioritise the interests of the Lottery.
They said current projections suggest the first repayment to the Lottery will not be until the mid-2020s.
A group of MPs have issued a warning to the public and private sector to protect the legacy of London 2012, from maintaining the volunteering spirit to ensuring that a £2bn Lottery donation is repaid.
The Public Accounts Committee said lessons can still be learned from the Games despite the country's "undoubted triumph" in hosting the Olympics and Paralympics.
The MPs said too few tickets were made available to the public for the box office Olympic events and described the pre-Games G4S security fiasco as a "sorry episode" and "notable blemish" on Britain's hosting duties.