Vincenzo has been transformed from a patient so sick he could not wash his face to a man who strides confidently with a gleam in his eye.
A look at organ donation rates around the world and how the UK compares.
In a one hour special the Tonight programme investigates the lives of the 10,000 Brits on waiting lists for an organ transplant.
Since the launch of the From the Heart campaign on Monday 120,000 people have signed up to the donor registry.
In the latest in ITV News' series of reports, From The Heart focuses on the extraordinary medical technology that keeps patients alive - while they wait for the heart transplant they so desperately need.
As ITV News' medical editor Lawrence McGinty reports from Papworth Hospital, the shortage of donors means that it is sometimes a long wait:
As part of the ITV1 special 'From the Heart' X Factor winner Alexandra Burke described how her family kept her mother's illness from her during the 2008 final of the X Factor.
Alexandra's mother Melissa needs a kidney transplant, and spends 8 hours a day on a dialysis machine, as she waits for one.
The severe shortage of Black, Asian and Minority Ethnic organ donors mean that donors from these communities have to wait three times longer to get the transplant they need.
The NHS website where people can register to be organ donors is experiencing difficulties due to an "overwhelming demand" from people watching the ITV 'From the Heart' Tonight special.
Public opinion is firmly divided on whether organ donation should be opt-in, as it currently is in the UK, or opt-out, as it is in many other European countries, according to an ITV News poll by ComRes. Older people are more likely to agree with the current 'opt-in' system.
- 44% agree with the current system: it should be presumed that people have not agreed to donate their organs, unless they have opted to do so.
- 42% think we should adopt a system were consent is presumed: people's organs should be donated, unless they have expressly opted-out of doing so.
- Among those aged 65 and over, 50% think organs should not be donated unless consent is expressly given.
ComRes surveyed 2,055 people.
Half of the population believe the family should always have the final say on whether a relative's organs are donated, according to the latest poll conducted by ComRes for ITV News.
- 49% think the family should always have the final say on whether or not their relative's organs are donated.
- 38% disagree that the family should always have final say on the matter.
- 13% aren't sure.
- 47% think that after the death of a loved one, it should be assumed that organs will be donated, unless the family have an objection.
- Men are more likely than women to agree that the family should always have the final say: 52% versus 45%
ComRes surveyed 2,055 people in total.