At least three armed men broke into the Bacha Khan University in northwest Pakistan and opened fire at students, according to reports.
The gunmen entered the university in Khyber Pakhtunkhwa province and opened fire at students and teachers in classrooms and hostels, the Reuters news agency says, citing local TV stations.
Police say they have heard at least two explosions and firing was still ongoing inside the campus. The army has now surrounded the campus.
Some reports suggest several people have been injured, but this has not been confirmed.
The attack comes just over a year since the Taliban stormed a school in the city of Peshawar, killing 134 students.
A suicide bomber has reportedly killed at least five people and wounded 20 more at a checkpoint in north-western Pakistan, according to Reuters.
The blast took place in Pakistan's Federally Administered Tribal Areas, where forces are fighting the Pakistani Taliban and other militants along the frontier with Afghanistan.
Officials say rescue workers have started evacuating the wounded to hospital in the nearby city of Peshawar.
At least 14 people have died in a bomb blast near a polio vaccination centre in the city of Quetta, Pakistan, police say.
Indian troops have killed four gunmen who entered an air force base near the border with Pakistan and exchanged fire with security forces. At least two soldiers also died in the firefight.
The gunmen entered the living quarters of the Pathankot air force base, about 267 miles north of New Delhi, said air force spokeswoman Rochelle D'Silva.
Pathankot, in Punjab state, is on the road that connects India's insurgency-wracked Jammu and Kashmir state with the rest of the country. It is also very close to India's border with rival Pakistan.
It comes as Indian Prime Minister Narenda Modi made an impromptu visit to Pakistan in an attempt to revive political dialogue between the two countries in late December.
India's home minister Rajnath Singh said India wanted peace with Pakistan but "if there is any kind of terror attack on India, we will give it a fitting reply".
A suicide bomber has killed at least 21 people and wounded dozens more in an attack on a government office in Pakistan, officials have said.
More than 70 people are believed to have been injured in the blast at a branch of the National Database and Registration Authority, which issues government identification cards, in the city of Mardan in Khyber Pakhtunkhwa province.
Police officer Naeem Khan said the bomber had been riding a motorcycle laden with explosives, which he detonated at the office.
A Pakistani Taliban faction has claimed responsibility for the attack.
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A 5.9 magnitude earthquake has hit Pakistan, near the border with Afghanistan, the United States Geological Survey said.
The quake struck 50 miles north-west of Chitral.
The death toll from a factory collapse in Pakistan has risen to 44, officials say.
According to the district health officer in Lahore sniffer dogs are now on the site of the building collapse trying to find more survivors after more than 100 injured workers were pulled from the rubble in the past five days.
Dr Zulfiqar Ahmad told Reuters: "Only the ground floor is left ... It will take another day to clear all the rubble, after which we will be in a better position to tell the final death toll.
"Today ... the whole operation was stopped for 45 minutes and a pin drop silence was maintained to hear sounds through voice sensors. But we found nothing."
Factory officials have said there were 160 to 175 factory workers, plus additional construction workers inside the factory when it collapsed in what is reportedly "one of the country's deadliest industrial accidents in recent years"
A total of 311 people have now been confirmed dead after a major earthquake hit the mountainous regions of south Asia.
The figure includes 237 people who died in Pakistan and 74 in Afghanistan. The death toll is expected to rise as rescuers are able to reach remote villages and areas cut off by landslides.
The death toll from a devastating earthquake which rocked northern Afghanistan and Pakistan has risen to "at least" 275.
Thousands of people have braved near-freezing temperatures and spent the night outdoors, for fear of more buildings coming down in further aftershocks.
Hundreds of buildings were destroyed as the initial magnitude 7.5 quake struck on Monday afternoon, followed by seven aftershocks which measured as high as 4.8 on the Richter scale.
The figure includes 228 people killed in Pakistan - and the death toll is expected to rise in the coming days as rescue workers make their way to difficult, remote mountain villages where communication are down.
Operations have been hampered by the possibility of landslides making the terrain even more dangerous, as well as security concerns as the region is suffering an escalating Taliban insurgency.