Paula Radcliffe, who missed out on competing at the London 2012 Olympics due to injury, said she is "looking forward" to the National Lottery Anniversary Run later today:
Marathon world record-holder Paula Radcliffe will run the first event to be staged at London's Olympic Stadium since the 2012 Games later today.
Radcliffe, who was unable to compete at the London Olympics due to injury, will join a host of sporting stars including Olympic gold medallists Sir Chris Hoy and Victoria Pendleton, who are more used to cycling than running.
They will be among the 12,500 people taking part in the five-mile (eight-kilometre) National Lottery Anniversary Run, in which competitors will complete the final 328 yards (300m) on the Olympic Stadium's track.
Radcliffe has predicted the event would "recapture the spirit of the London 2012".
Marathon world record-holder Paula Radcliffe is to run in the first event to be staged at London's Olympic Stadium since the 2012 Games.
Radcliffe, who was unable to compete at the London Olympics due to injury, will join 12,500 people in the five-mile (eight-kilometre) National Lottery Anniversary Run on July 21.
Competitors will complete the final 328 yards (300m) on the Olympic Stadium's track after they have made their way round the Queen Elizabeth Park in Stratford, east London.
Radcliffe, who will be joined by gold medallist Victoria Pendleton, predicted the event would "recapture the spirit of the London 2012".
Paula Radcliffe, Iwan Thomas and British Athletics have congratulated Olympic gold medallist Jessica Ennis on her wedding to long-term partner Andy Hill:
Congratulations @j_ennis lots more fun and happy times ahead. Looking gorgeous both of you.
@j_ennis congrats to you and Andy x
World marathon record holder Paula Radcliffe has admitted that she may never compete again because of ongoing complications with her foot injury.
The 39-year-old was forced to pull out of the 2012 Olympics shortly before the Games, despite having had specialist treatment in Germany in July.
Radcliffe underwent surgery in August when it emerged her foot problems were more serious than first thought and it was then she entertained a future without competition.
However, she still had hopes of ending her career with at least one more competitive outing, but knows it is not guaranteed.
Radcliffe told BBC Sport: "Targets have gone out of the window.
"I'm very much in that limbo where I know and accept that realistically it may not be possible.
"But at the same time I have a little window of hope and I would rather be able to finish my career in a race, rather than a race I can't actually get to the start line of."
Scottish long-distance runner Freya Murray will replace Paula Radcliffe in the London 2012 Olympic marathon, reports Sky Sports News and Sky News Olympics Producer Lia Hervey.
Two-time Olympic gold medallist Daley Thompson has described Paula Radcliffe as "one of the greatest athletes we (Great Britain) has ever produced".
The world record marathon holder had to withdraw from the London 2012 Games with a foot injury on Sunday.
Paula Radcliffe if u do retire its as one of the greatest athletes we have ever produced. The only thing u lacked in you armory was luck
First time I smiled today was watching @l_armitstead claim silver in the womens road race - well done!
Paula Radcliffe continued: "Yes, I made more commitment than ever in preparation this year, two months away from the three most important people in my life.
Every single athlete out there makes the same commitments, puts their all into their preparation, and sadly I am not the only one to suffer heartbreak in trying to go after our goals. The most important thing is, as I always believe, to know that you did all you could in going after those dreams.
It is hard to know that had the Olympics been six weeks earlier I could have gone out there and run confidently knowing that I was in the best shape I had been in for a while, but I am by no means the first to experience something like this.
No-one tells us in advance where the limits of our own bodies lie, and pushing these limits is the only way we can ever achieve our highest goals and dreams. However hard today is, finally closing the door on that dream, at least I can know that I truly have tried absolutely everything.
As desperate as I was to be part of the amazing experience of the London Olympics, I don't want to be there below my best. If I can't be there and give it my best, then I would rather someone else who can do that is able to be there."