One woman has died in a collision between a lorry and a minibus on its way to a hen party on the M62 near Pontefract, West Yorkshire Police said.
This photo, tweeted by Pritpal Singh, shows ambulances at the site of the crash on the M62.
Kevin Hodgson, director of operations at Great North Air Ambulance, said they had sent two air ambulances, which were joined by two from North West Air Ambulance and another two from Lincolnshire and Nottinghamshire Air Ambulance.
He said one helicopter had already landed at Leeds General Infirmary and one was en route to the James Cook University Hospital in Middlesbrough - each with one patient on board.
"We do not know the exact state of the injuries, but certainly the patient en route to the James Cook Hospital was anaesthetised on scene by the doctor and paramedic."
Mr Hodgson said it was unlikely the aircraft would return to the scene, as there were enough resources there to deal with the casualties.
Dave Walton, Assistant Chief Officer with West Yorkshire Fire and Rescue Service, has tweeted that the initial rescue phase for the M62 crash is now over, but that there is "more to do".
The driver of a lorry involved in a crash with a minibus on the M62 at Pontefract, which has left 19 people injured, six seriously, has been arrested in connection with the incident, West Yorkshire Police said today.
West Yorkshire Police have said that a total of 19 people from the crash on the M62 involving a minibus and a lorry have received injuries, six of them serious.
Emergency service sources have told ITV News Calendar that more than 20 people have been injured in the motorway crash involving a minibus and a lorry on the M62.