Former Everton striker Ayegbeni Yakubu showed his finishing prowess as Reading progressed to the last eight of the FA Cup at the expense of a Derby County side reduced to 10 men for 50 minutes.
Derby looked the better side until their full-back Stephen Warnock was sent off for a second yellow card in the 39th minute.
Hal Robson-Kanu's goal was cancelled out by Darren Bent but Yakubu, signed as a free agent during the January transfer window, netted the winner.
Yakubu could be on his way back to English football by signing for Championship side Reading.
The former Milddlesbrough frontman is a free agent having been released by Al Rayyan and would to the Madjeski on a deal until the end of the season.
Hal Robson-Kanu booked Reading's place in the fifth round of the FA Cup with a late winner in a 2-1 victory at Cardiff.
Wales international Robson-Kanu, on as an 82nd minute substitute, swept home Jordan Obita's cross six minutes later after Oliver Norwood had cancelled out Kenwyne Jones' first-half header for the Bluebirds.
Championship club Reading have appointed Steve Clarke as their new management.
The former West Brom manager and Chelsea number two replaces Nigel Adkins, who was sacked following a dismal 6-1 defeat against Birmingham.
Clarke said: “I am absolutely delighted to be joining Reading Football Club and I look forward to helping the club move in the right direction. A big part of the work ahead is on the training ground and I look forward to meeting the players and getting onto the grass with them.
"There is real potential here and hopefully exciting times ahead for the supporters.”
Reading and QPR have both been relegated from the Barclays Premier League after their goalless draw at the Madejski Stadium today.
Reading Football Club have sacked manager Brian McDermott, a statement on the club's official website confirmed.
The Premier League club's owner, Anton Zingarevich said he felt a change was necessary.
McDermott guided the Royals to the top flight for only the second time in their history last season.
Reading are currently second from bottom in the Barclays Premier League table.