Refugee Council chief executive Maurice Wren said Britain has a proud tradition of protecting refugees and it must increase the opportunities afforded to those attempting to flee persecution.
The UK and wider EU can and should increase the number of resettlement places they provide.
Resettlement is a vital protection tool for refugees whose lives and liberty are at risk; a long term solution for refugees and an expression of solidarity with developing countries who host the majority of the world's refugees.
We must do all we can to help. For some children, a resettlement place in the UK would give them their first ever night's sleep on a mattress in a real bed, access to running water and simply, the hope of a better future.
David Cameron has been accused of "political posturing" after the Government confirmed plans to accept "several hundred" of the most vulnerable refugees from the Syrian conflict in a bid to head off a damaging backbench revolt.
The change of heart by the coalition - confirmed by Home Secretary Theresa May in a Commons statement ahead of an opposition day debate on the issue - was broadly welcomed by MPs on all sides of the House.
Tory backbencher Andrew Bridgen said Britain had already donated £600 million - more than the rest of the EU put together - and that admitting a few hundred people would make little difference to such a vast refugee crisis.
"It is pure political posturing and tokenism. I think that people can see the political expediency of the u-turn," he told BBC Radio 4's The World at One.
Home Secretary Theresa May has outlined the Government's plan to help the most vulnerable Syrians find safety in the UK.
She told the House of Commons: "Our country has a proud tradition of providing protection to those in need. And where there are particularly difficult cases of vulnerable refugees, who are at grave risk, we are ready to look at those cases."
She added: "The Government will be launching a new programme to provide emergency sanctuary in the UK for displaced Syrians who are particularly vulnerable."
Britain is to take in some of the most vulnerable refugees from the Syrian civil war.
The most vulnerable refugees include:
Victims of sexual assaults
The UK is not signing up to take a quota of refugees under the United Nations sanctuary scheme to resettle up to 30,000 vulnerable Syrians in Western nations, but Nick Clegg said the UN High Commission for Refugees backs the Government's plans.