Victims in the Rotherham child sexual exploitation case suffered "unthinkable physical and psychological" trauma, Peter Mann from the Crown Prosecution Service said following the verdicts.
He said: "These defendants in their differing ways targeted these teenage girls because they were vulnerable and then facilitated their systematic sexual abuse. The abusers then groomed and sexualised their victims, often subjecting them to acts of a degrading and violent nature.
"Some of the violence was extreme and protracted."
Mr Mann added: "Such depravity has no place in our society."
He also said Arshid Hussain played a key role in the sex ring and that his behaviour was "domineering" and "brutal".
Some of the 15 women who were victims of a child sex grooming ring in Rotherham were in court to see their abusers convicted today.
Three men - brothers Arshid and Basharat Hussain and Qurban Ali - and two women - Karen MacGregor and Shelley Davies - were found guilty at Sheffield Crown Court of a range of offences involving the sexual exploitation of teenage girls in the South Yorkshire town.
A fourth man - Bannaras Hussain - had admitted 10 charges including rape, indecent assault and assault occasioning actual bodily harm at the beginning of the trial.
During the trial, a jury of six men and six women had heard women describe how they were targeted in their young teens and subjected to brutal treatment as they were passed around men who raped and beat them.
Some described how they were trafficked, locked up, physically assaulted and threatened with death.
The Rotherham child sex exploitation verdicts are a "crucial milestone" for the victims of abuse, police have said.
Senior investigating officer Martin Tate said he was pleased those responsible had been held to account for the "systematic and organised sexual abuse of young girls".
Speaking outside Sheffield Crown Court, he said: "The verdict today marks a crucial milestone for those victims and survivors who endured years of violence and horrific sexual abuse at the hands of these vile individuals.
"I can't begin to put into words the trauma that these women experienced at such a young age."
Brothers Arshid and Basharat Hussain were found guilty of multiple rapes and indecent assaults of teenage girls as part of a child sex grooming gang in Rotherham following a trial.
A third brother, Bannaras Hussain, 36, admitted 10 charges including rape, indecent assault and assault occasioning actual bodily harm at the beginning of the trial at Sheffield Crown Court.
Their uncle Qurban Ali, 53, was cleared of all the charges he faced except one of conspiracy to rape.
Two women - Karen MacGregor, 58, and Shelley Davies, 40 - were found guilty of conspiracy to procure prostitutes and false imprisonment following the trial.
Meanwhile brothers Majid Bostan, 37 and Sajid Bostan, 38, were cleared of all charges following the trial.
Three men and two women have been found guilty at Sheffield Crown Court of a range of offences involving the sexual exploitation of teenage girls in Rotherham.
Two other defendants were cleared of all charges.
Only a few of the 1,400-plus victims who were sexually exploited in Rotherham have come forward for help, a lawyer has said.Read the full story ›
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The police service at the centre of the Rotherham exploitation scandal still needs to make 'major improvements' in child protection.Read the full story ›
'Emma' told ITV News there could be more than the 300 possible suspects police have identified.Read the full story ›
A new investigation into child sexual exploitation in Rotherham has identified around 300 possible suspects.
Those suspected of being part of a network who abused at least 1,400 children over a 16-year period is said to include two former or serving councillors.
The National Crime Agency said its inquiry into allegations of child sexual exploitation in the town has the potential to identify "thousands of offences".
The investigation, called Operation Stovewood, was set up last year following Professor Alexis Jay's damning report into abuse by largely Asian men in the South Yorkshire town.