Police are appealing for information on two men seen running away from the scene of the shooting on Hindrey Road, towards the nearby Pembury Estate.
One is black, officers said, while the second is light-skinned, possibly of Asian or Turkish appearance.
Police said there was as yet no clear motive for the shootings, and no-one has been arrested.
"At this very early stage we must retain an open mind regarding the circumstances of the incident and any motive," the spokesman said.
A Metropolitan Police spokesman said the teenager died at about 11.10pm.
Police said there was no clear motive for the shootings yet and no-one has been arrested.
Witnesses to the shooting or anyone with information about the incident are asked to call police on 101 or Crimestoppers on 0800 555 111.
A teenager has died and a man is fighting for his life after they were gunned down in a street.
The pair were shot in Hindrey Road, Clapton, east London, at 8.20pm yesterday, Scotland Yard said.
Paramedics rushed them to hospital where the younger victim, 19, died. A 22-year-old man was understood to be in a stable condition, police said.
A woman has been shot dead in Hinckley, Leicestershire, Leicestershire Police have confirmed.
Police were called to an address in Sunnydale Road at 10.14pm on Sunday night following reports that a woman had been shot.
Police found a woman who had been shot and she was declared dead at the scene.
A man has been arrested and is in custody.
Two people have died, and a teenager has been left wounded in a shooting in eastern Kentucky, the Press Association reports.
The shooting happened yesterday afternoon in the car park of Hazard Community and Technical college in Hazard.
According to Conor Duff, the college's evening co-ordinator, the shootings took place at 4.30pm (9.30pm GMT) at the campus.
He added that police had searched the school's buildings to check no one else was at risk.
Shortly after, the school was on lockdown, although the school's website reports it has since been reopened.
Special police units and local police forces were alerted by a caller who said several people were lying wounded on the ground at about 8:50 p.m. (1950 GMT), the police statement said.
It said the incident was being investigated and the site had been closed off. More information would be released later today at a news conference in the village, which is close to the town of Sion, the capital of the canton - or region - of Valais.
Mass shootings are rare in Switzerland, although gun possession is widespread - some estimates run to at least one for every three of its 8 million inhabitants. Many are stored in people's attics, a legacy of Switzerland's policy of arming its men to defend its neutrality.
Three people were killed and two wounded late on Wednesday when a gunman opened fire in the Swiss village of Daillon, Swiss police said. When police tried to arrest him, the suspect threatened them, before officers shot and wounded him and took him into custody.
Police of the Swiss canton of Valais said in a statement that no officers were wounded.
A US man has been arrested for allegedly shooting in the direction of a fellow barber shop customer after a dispute about the Newtown school shooting, US media have reported.
Lester Davis, 57, allegedly fired at a man who reportedly said he wanted to kill the suspect in the Sandy Hook Elementary School shooting.
Police say Davis, for unknown reasons, took the remark as a threat and asked, "You want to murder me?"
Davis then allegedly got a pistol from his car and fired three times in the customer's direction.
No one was hurt in the incident at the All Cuts barber shop in Wentzville, Missouri on Tuesday.
US police say two people are dead and another is injured after a shooting at a central Florida Veterans of Foreign Wars post.
Winter Springs Police said a charity motorcycle ride was supposed to depart from the post when the shooting broke out on Sunday morning while the riders were eating breakfast.
Local papers reported an unknown number of armed men came in and began firing.
It's unclear if anyone shot back.
Veterans of Foreign Wars posts around the country care for veterans and their families.