Manchester Airport have reported minor delays as a result of continued air traffic control problems.
The airport advised passengers to check with their airline about the continuing delays.
EasyJet advised passengers to check in for flights as normal "as the situation can improve", but suggested they refer to the airline's flight tracker page for updates.
A message on its website read: "Although this is beyond easyJet's control, we apologise for any inconvenience that you may experience today."
A spokesman for Cardiff Airport said all flights this morning had been affected.
Heathrow Airport have said there have been cancellations for flights scheduled to leave this morning after a technical problem at the air traffic control centre.
A Heathrow Airport spokeswoman said: "We are currently experiencing some delays."
Flight information on the airport's website showed several departures to both domestic and international destinations had been cancelled.
Departing flights from Gatwick and Stansted are facing delays of up to two hours after issues within UK air traffic control.
A Stansted spokesman said all departing flights are subject to delays of between 30 minutes and two hours.
Gatwick Airport said 20 per cent of its departures were experiencing delays, with passengers warned they could wait for a "couple of hours".
The airport said there were currently no issues with arrivals.
Passengers are advised to check with their airline for the latest situation.