For more than a decade, experts have known that olfactory ensheathing cells (OECs) might prove useful in treating damaged spinal cords.
The cells support nerve fibre growth that maintains a communication pathway between the nose and the brain.
Previous research suggests that OECs can help form a bridge between damaged and undamaged spinal cord tissue by regenerating nerve fibres.
Although the treatment had been shown to be safe in human patients, its effectiveness was unknown.
In the new trial, scientists studied 34 pet dogs that had all suffered spinal cord injuries as a result of accidents and back problems. None were injured deliberately for the sake of research.
A year or more after their injuries, the animals were unable to use their back legs to walk and incapable of feeling pain in their hindquarters.
A study of pet dogs with severe spinal injuries suffered in accidents offers new hope for paralysed human patients.
Scientists restored movement to the dogs' hind legs by bridging breaks in the spinal cord using cells taken from their noses.
The video shows previously crippled dachshund, Jasper, during the course of the treatment:
Scientists studied 34 dogs that had all suffered spinal cord injuries as a result of accidents and back problems.
Professor Robin Franklin, one of the study leaders from Cambridge University, said
Our findings are extremely exciting because they show for the first time that transplanting these types of cell into a severely damaged spinal cord can bring about significant improvement.
Scientists have restored movement to the hind legs of dogs with severe spinal injuries by injecting them with cells grown from the lining of their nose.
Jasper, a previously crippled dachshund, was described by his owner of "whizzing around the house" after undergoing the treatment.
The trial is the first to demonstrate effective spinal cord repair in "real life" injury cases, offering new hope for paralysed human patients.
Rachael Stevens explains how Retinitis Pigmentosa effects her and how she is "extraordinarily excited" by the breakthrough in research.
Professor Robin Ali explains how a study on mice could help treat patients suffering from Retinitis Pigmentosa: