Heather Watson was knocked out of the Seoul Open at the first hurdle as she lost 6-3 0-6 6-1 to Sara Sorribes Tormo.
Briton Watson, who had moved back into the top 100 after reaching the third round at Wimbledon, has now failed to get past the first round in Korea in four attempts.
Sorribes Tormo, ranked 14 places lower than Watson, broke serve four times in the final set to advance after one hour and 36 minutes.
The Spaniard will now take on third seed Kristyna Pliskova or local wildcard Han Na-lae in the next round.
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Andy Murray is unlikely to play again this season due to the hip injury that forced him to miss the US Open.
Murray has ruled himself out of the forthcoming tournaments in Beijing and Shanghai and also expects to sit out the season-ending events in Vienna and Paris.
"Having consulted with a number of leading hip specialists over the last week, along with my own team, we have decided that this is the best decision for my long-term future," Murray wrote on Facebook.
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