Andy Murray suffered his worst grand slam defeat since losing to Stanislas Wawrinka in the third round in New York three years ago.
Speaking at post-match press conference a visibly disappointed Murray said: "I don't think I was playing poorly. I got to the quarter-finals of a slam which isn't easy.
"I would have liked to have played a little bit better but I've had a good run the last couple of years. It's a shame I had to play a bad match today."
Reigning US Open champion Andy Murray crashed out of this year's tournament in the quarter-finals after suffering a defeat in straight sets to Switzerland's Stanislas Wawrinka.
The ninth seed beat Britain's number one 6-4 6-3 6-2.
Andy Murray is fighting to stay in the US Open after losing the first two sets of his quarter final match against Switzerland's Stanislas Wawrinka.
The defending champion lost the opening two sets 6-4 6-3.
Andy Murray has secured his place in the quarter finals of the US Open after beating Denis Istomin of Uzbekistan. The final score was: 6-7 (5-7) 6-1 6-4 6-4.
Swiss tennis player Roger Federer has been beaten by Spain's Tommy Robredo in the fourth round of the US Open tournament in New York.
In a stunning upset, Robredo won in straight sets: 7-6(3) 6-3 6-4
British number three seed Dan Evans was knocked out of the US Open today by Spaniard Tommy Robredo, but tweeted following the match in which he lost in four sets.
Be good if I could feel my toes!
Britain's tennis sensation Dan Evans has been beaten by Spaniard Tommy Robredo in the third round of the US Open. Robredo beat Evans 7-6 (8-6) 6-1 4-6 6-5.
British tennis champion Andy Murray has been following new sensation Dan Evans during his third round match at the US Open.
Evo should be so proud whatever happens from now,amazing fighting,great attitude ,looks fresher than trob.. Never though that would happen!
Britain's new tennis sensation, Dan Evans, will take on Spaniard Tommy Robredo in the third round of the US Open.
The Birmingham man has surprised the tennis world with his performances so far at this year's tournament - which he only qualified for because another player dropped out.
His defeat of 11th seed Kei Nishikori in the first round earlier this week was Evans' first ever US Open match.
He followed that up by defeating Australian, Bernard Tomic, yesterday - a player whose father blocked a practice session with Evans, claiming he was not good enough.
Nineteenth seed Tommy Robredo beat Marinko Matosevic in four sets in his first round match, and dominated Frank Dancevic in the second round in straight sets.
The sister of the British number three Dan Evans has told Daybreak his success at the US Open is the result of "maturity."
She and her family "broke down in tears" with "complete and utter elation" at Evans' four set win over Bernard Tomic yesterday.