The Welsh Ambulance Service has confirmed it attended a traffic collision on Fontgary Road in Rhoose at 8:55am.
The spokesperson added there are no details yet regarding the severity of the injuries.
Local MP for the Vale of Glamorgan Alun Cairns has said that there were no fatalities after a car overturned near a primary school in south Wales:
ITV Wales is reporting that an overturned black Audi is at the scene of the accident near a school in south Wales.
Residents report hearing a 'loud noise' shortly before nine. Witnesses also report seeing a lollipop lady lying on the ground.
An Air Ambulance, which was at the scene, is understood to have just left.
Vale of Glamorgan MP Alun Cairns says he is 'liaising with police' following this morning's collision in Rhoose.
Police say children are among those injured.
Glenys Watson, who works at a cafe on the same road as the school, said the scene was "like a war zone".
"I've never seen so many police cars," she told the BBC.
Three rapid response vehicles and five emergency ambulances were sent to the scene, where there were "multiple casualties", a spokeswoman for Welsh Ambulance Services NHS Trust said.
She added the ambulance service was called to the single vehicle collision at about 8.55am this morning.
The primary school is in the village of Rhoose, approximately five miles outside Barry in the Vale of Glamorgan.
The school also has a nursery unit.
Police have said a car overturned outside the school and that casualties have been taken to hospital.