Johanna Konta's defence of her Miami Open title ended on Monday as Venus Williams beat the British number one 5-7 6-1 6-2 in their fourth-round match in Key Biscayne.
The result will see 11th seed Konta drop from 14th in the world rankings to outside the top 20.
Williams, making her 19th appearance at the tournament and reaching the quarter-finals for a 13th time, enjoyed the vocal home support as she produced an outstanding display after coming off second best in a wobbly opening set.
The 37-year-old will face fellow American Danielle Collins in the last eight. Collins triumphed 3-6 6-4 6-2 against Puerto Rico's Monica Puig, who had seen off world number two Caroline Wozniacki at the weekend.
Spanish third seed Garbine Muguruza followed Konta out of the tournament, with Sloane Stephens winning 6-3 6-4. Stephens - seeded 13 - will next play 10th seed Angelique Kerber, who rallied for a hard-fought 6-7 (1/7) 7-6 (7/5) 6-3 victory over China's Yafan Wang.
Two-time Wimbledon champion Petra Kvitova was sent packing in the late match, with French Open champion Jelena Ostapenko seeing off the rain as well as the ninth-seeded Czech. The Latvian fifth seed prevailed 7-6 (7/4) 6-3 to reach the last eight, where she will take on Ukraine's Elina Svitolina.
Fourth seed Svitolina overcame Australian Ashleigh Barty 7-5 6-4.
Fifth seed Karolina Pliskova was leading Zarina Diyas 6-2 2-1 when the Kazakh retired injured. The Czech will next take on Victoria Azarenka, who overpowered fellow former Miami champion Agnieszka Radwanska 6-2 6-2.
Venus Williams got the better of her younger sister Serena to make it through to the fourth round at Indian Wells with a 6-3 6-4 win.
Serena was playing in her first tournament since giving birth last September and faced her sister for the 29th time, with Venus winning all but four of their meetings.
Serena saved three break points to hold her first service game but lost her third to love as Venus took a 4-2 lead and served out for the set in 37 minutes.
Venus raced to a 3-0 lead in the second set after breaking her sister twice and had a match point at 5-3 which Serena saved, before Venus saved a break point of her own at 5-4 and went on to take the match.
The number eight seed will go on to face Latvian Anastasija Sevastova who beat Julia Goerges in straight sets 6-3 6-3.
Second seed and Australian Open champion Caroline Wozniacki is through to the fourth round after seeing off Aliaksandra Sasnovich 6-4 2-6 6-3, while US Open champion Sloane Stephens lost to Daria Kasatkina 6-4 6-3.
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Serena Williams returned to Centre Court to win her second Wimbledon title of the day as she and sister Venus triumphed in the doubles final.
Their sixth Wimbledon success as a team came at the expense of Yaroslava Shvedova and Timea Babos, with the Williams pairing earning a 6-3 6-4 victory.
Between beating Angelique Kerber in straight sets to take the singles title and being called to the court for the doubles, Serena Williams had paraded her trophy, signed autographs, held a press conference and conducted television interviews.
But the 34-year-old and her 36-year-old sister showed little sign of distraction as they were comfortable winners against Kazakh player Shvedova and Hungarian Babos, Serena Williams putting away the match-winning backhand volley at the net.
Venus Williams rolled back the years to reach her first grand slam semi-final since 2010 as the American beat Kazakhstan's Yaroslava Shvedova at Wimbledon.
Williams, who turned 36 last month, is the oldest woman competing at the All England Club but her recent resurgence continued on Centre Court with a 7-6 (7/5) 6-2 victory.
The five-time Wimbledon champion has not made the last four at a major tournament since the US Open six years ago and she will now face Germany's Australian Open champion Angelique Kerber for a place in the final.
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Top seed Serena Williams advanced to the quarter-finals of the Miami Open as Venus Williams upset fourth seed Caroline Wozniacki.
Serena beat 24th seed Svetlana Kuznetsova 6-2 6-3, while her elder sister Venus, who is the 16th seed, beat former world number one Wozniacki of Denmark 6-3 7-6 (7/1).
Venus will play Carla Suarez Navarro, the 12th seed, in the last eight after the Spaniard saw off seventh seed Agnieszka Radwanska of Poland 5-7 6-0 6-4.
Next up for Serena is a clash with Sabine Lisicki of Germany after her 6-1 6-2 defeat of Italy's Sara Errani.